A new active contour model for finding and mapping the outer cortex in brain images is developed. A cross-section of the brain cortex is modeled as a ribbon, and a constant speed mapping of its spine is sought. A variational formulation, an associated force balance condition, and a numerical approach are proposed to achieve this goal. The primary difference between this formulation and that of snakes is in the specification of the external force acting on the active contour. A study of the uniqueness and fidelity of solutions is made through convexity and frequency domain analyses, and a criterion for selection of the regularization coefficient is developed. Examples demonstrating the performance of this method on simulated and real data are provided.

A general active contour formulation is considered and a convexity analysis of its energy function is presented. Conditions under which this formulation has a unique solution are derived; these conditions involve both the active contour energy potential and the regularization parameters. This analysis is then applied to four particular active contour formulations, revealing important characteristics of their convexity, and suggesting that external potentials involving center of mass computations may be better behaved than the ususal potentials based on image gradients. Most importantly, our analysis provides an explanation for the poor convergence behavior at concave boundaries and suggests an alternate algorithm for approaching these types of boundaries. I. Introduction Active contours, originally described by Kass, Witkin, and Terzopoulos [1], have been successfully used in a wide variety of applications. Their main advantage is that they are topologically isomorphic to the feature...