Locally weighted polynomial regression (LWPR) is a popular instance-based algorithm for learning continuous non-linear mappings. For more than two or three inputs and for more than a few thousand datapoints the computational expense of predictions is daunting. We discuss drawbacks with previous approaches to dealing with this problem, and present a new algorithm based on a multiresolution search of a quicklyconstructible augmented kd-tree. Without needing to rebuild the tree, we can make fast predictions with arbitrary local weighting functions, arbitrary kernel widths and arbitrary queries. The paper begins with a new, faster, algorithm for exact LWPR predictions. Next we introduce an approximation that achieves up to a two-ordersof -magnitude speedup with negligible accuracy losses. Increasing a certain approximation parameter achieves greater speedups still, but with a correspondingly larger accuracy degradation. This is nevertheless useful during operations such as the early stages...