Single molecules perform a variety of tasks in cells, from replicating, controlling and translating the genetic material to sensing the outside environment. These operations all require that specific actions take place. In a sense, each molecule must make tiny decisions. To make a decision, each “molecular machine ” must dissipate an energy Py in the presense of thermal noise Ny. The number of binary decisions that can be made by a machine which has dspace

Schneider, T. D. (1991). Theory of molecular machines. I. Channel capacity

This paper provides an overview of research developments toward nanometer-scale electronic switching devices for use in building ultra-densely integrated electronic computers. Specifically, two classes of alternatives to the field-effect transistor are considered: 1) quantum-effect and single-electron solid-state devices and 2) molecular electronic devices. A taxonomy of devices in each class is provided, operational principles are described and compared for the various types of devices, and the literature about each is surveyed. This information is presented in nonmathematical terms intended for a general, technically interested readership

Abstract: The structural, coordinative, photochemical and electrochemical properties of the porphyrin macrocycle that make them the functional element of choice in ubiquitous biological systems, e.g., chlorophyll, cytochrome P450 and hemoglobin, also contribute to making porphyrins and metalloporphyrins desirable in a “bottom-up ” approach to the construction of nanosized devices. This paper highlights some recent advances in the construction of supramolecular assemblies based on the porphyrin macrocycle that display optically readable functions as a result of photonic or chemical stimuli.

Molecular nanotechnology has matured in the last thirty-nine years from the germ of an idea by a Nobel Laureate physicist to a rapidly growing international research site with more than $1 billion dollars in annual investment. Although only recently accepted as “mainstream” by the R&D community, nanotechnology research is now populated by eminent researchers in such fields as physics, chemistry, molecular biology, and computer science. Refereed journal articles appear with increasing frequency. The National Academy of Sciences, the RAND Corporation, the Department of Defense, and the National Science Foundation have recently issued reports calling for more structure and organization in nanotechnology research to improve synergy and research efficiency. Others insist that centralization would restrict independent approaches, one of which might be the best path to follow. This thesis addresses the following issues for the emerging field of molecular nanotechnology: The field is extensive, growing, and in need of policy review. The parties responsible for strategic science and technology policy in the United States as well as the current infrastructure for R&D funding are identified.

Virtually all molecular electronic devices rely on the interplay between spatial organization and electronic motion to attain the resolution and responsiveness neces-sary for practical applications.1 An efficient optical com-