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685
Approaches for Bayesian variable selection
 Statistica Sinica
, 1997
"... Abstract: This paper describes and compares various hierarchical mixture prior formulations of variable selection uncertainty in normal linear regression models. These include the nonconjugate SSVS formulation of George and McCulloch (1993), as well as conjugate formulations which allow for analytic ..."
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Cited by 124 (5 self)
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Abstract: This paper describes and compares various hierarchical mixture prior formulations of variable selection uncertainty in normal linear regression models. These include the nonconjugate SSVS formulation of George and McCulloch (1993), as well as conjugate formulations which allow for analytical simplification. Hyperparameter settings which base selection on practical significance, and the implications of using mixtures with point priors are discussed. Computational methods for posterior evaluation and exploration are considered. Rapid updating methods are seen to provide feasible methods for exhaustive evaluation using Gray Code sequencing in moderately sized problems, and fast Markov Chain Monte Carlo exploration in large problems. Estimation of normalization constants is seen to provide improved posterior estimates of individual model probabilities and the total visited probability. Various procedures are illustrated on simulated sample problems and on a real problem concerning the construction of financial index tracking portfolios.
MCMCbased particle filtering for tracking a variable number of interacting targets
 IEEE Transactions on Pattern Analysis and Machine Intelligence
, 2005
"... We describe a particle filter that effectively deals with interacting targets targets that are influenced by the proximity and/or behavior of other targets. The particle filter includes a Markov random field (MRF) motion prior that helps maintain the identity of targets throughout an interaction, s ..."
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Cited by 117 (6 self)
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We describe a particle filter that effectively deals with interacting targets targets that are influenced by the proximity and/or behavior of other targets. The particle filter includes a Markov random field (MRF) motion prior that helps maintain the identity of targets throughout an interaction, significantly reducing tracker failures. We show that this MRF prior can be easily implemented by including an additional interaction factor in the importance weights of the particle filter. However, the computational requirements of the resulting multitarget filter render it unusable for large numbers of targets. Consequently, we replace the traditional importance sampling step in the particle filter with a novel Markov chain Monte Carlo (MCMC) sampling step to obtain a more efficient MCMCbased multitarget filter. We also show how to extend this MCMCbased filter to address a variable number of interacting targets. Finally, we present both qualitative and quantitative experimental results, demonstrating that the resulting particle filters deal efficiently and effectively with complicated target interactions.
Sensitivity and specificity of inferring genetic regulatory interactions from microarray experiments with dynamic Bayesian networks
 Bioinformatics
, 2003
"... Motivation: Bayesian networks have been applied to infer genetic regulatory interactions from microarray gene expression data. This inference problem is particularly hard in that interactions between hundreds of genes have to be learned from very small data sets, typically containing only a few doze ..."
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Cited by 109 (3 self)
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Motivation: Bayesian networks have been applied to infer genetic regulatory interactions from microarray gene expression data. This inference problem is particularly hard in that interactions between hundreds of genes have to be learned from very small data sets, typically containing only a few dozen time points during a cell cycle. Most previous studies have assessed the inference results on real gene expression data by comparing predicted genetic regulatory interactions with those known from the biological literature. This approach is controversial due to the absence of known gold standards, which renders the estimation of the sensitivity and specificity, that is, the true and (complementary) false detection rate, unreliable and difficult. The objective of the present study is to test the viability of the Bayesian network paradigm in a realistic simulation study. First, gene expression data are simulated from a realistic biological network involving DNAs, mRNAs, inactive protein monomers and active protein dimers. Then, interaction networks are inferred from these data in a reverse engineering approach, using Bayesian networks and Bayesian learning with Markov chain Monte Carlo.
Results: The simulation results are presented as receiver operator characteristics curves. This allows estimating the proportion of spurious gene interactions incurred for a specified target proportion of recovered true interactions. The findings demonstrate how the network inference performance varies with the training set size, the degree of inadequacy of prior assumptions, the experimental sampling strategy and the inclusion of further, sequencebased information.
Benchmark Priors for Bayesian Model Averaging
 FORTHCOMING IN THE JOURNAL OF ECONOMETRICS
, 2001
"... In contrast to a posterior analysis given a particular sampling model, posterior model probabilities in the context of model uncertainty are typically rather sensitive to the specification of the prior. In particular, “diffuse” priors on modelspecific parameters can lead to quite unexpected consequ ..."
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Cited by 94 (5 self)
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In contrast to a posterior analysis given a particular sampling model, posterior model probabilities in the context of model uncertainty are typically rather sensitive to the specification of the prior. In particular, “diffuse” priors on modelspecific parameters can lead to quite unexpected consequences. Here we focus on the practically relevant situation where we need to entertain a (large) number of sampling models and we have (or wish to use) little or no subjective prior information. We aim at providing an “automatic” or “benchmark” prior structure that can be used in such cases. We focus on the Normal linear regression model with uncertainty in the choice of regressors. We propose a partly noninformative prior structure related to a Natural Conjugate gprior specification, where the amount of subjective information requested from the user is limited to the choice of a single scalar hyperparameter g0j. The consequences of different choices for g0j are examined. We investigate theoretical properties, such as consistency of the implied Bayesian procedure. Links with classical information criteria are provided. More importantly, we examine the finite sample implications of several choices of g0j in a simulation study. The use of the MC3 algorithm of Madigan and York (1995), combined with efficient coding in Fortran, makes it feasible to conduct large simulations. In addition to posterior criteria, we shall also compare the predictive performance of different priors. A classic example concerning the economics of crime will also be provided and contrasted with results in the literature. The main findings of the paper will lead us to propose a “benchmark” prior specification in a linear regression context with model uncertainty.
A SplitMerge Markov Chain Monte Carlo Procedure for the Dirichlet Process Mixture Model
 Journal of Computational and Graphical Statistics
, 2000
"... . We propose a splitmerge Markov chain algorithm to address the problem of inefficient sampling for conjugate Dirichlet process mixture models. Traditional Markov chain Monte Carlo methods for Bayesian mixture models, such as Gibbs sampling, can become trapped in isolated modes corresponding to an ..."
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Cited by 91 (0 self)
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. We propose a splitmerge Markov chain algorithm to address the problem of inefficient sampling for conjugate Dirichlet process mixture models. Traditional Markov chain Monte Carlo methods for Bayesian mixture models, such as Gibbs sampling, can become trapped in isolated modes corresponding to an inappropriate clustering of data points. This article describes a MetropolisHastings procedure that can escape such local modes by splitting or merging mixture components. Our MetropolisHastings algorithm employs a new technique in which an appropriate proposal for splitting or merging components is obtained by using a restricted Gibbs sampling scan. We demonstrate empirically that our method outperforms the Gibbs sampler in situations where two or more components are similar in structure. Key words: Dirichlet process mixture model, Markov chain Monte Carlo, MetropolisHastings algorithm, Gibbs sampler, splitmerge updates 1 Introduction Mixture models are often applied to density estim...
Bayesian Methods for Hidden Markov Models  Recursive Computing in the 21st Century
 JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
, 2002
"... Markov chain Monte Carlo (MCMC) sampling strategies can be used to simulate hidden Markov model (HMM) parameters from their posterior distribution given observed data. Some MCMC methods (for computing likelihood, conditional probabilities of hidden states, and the most likely sequence of states) use ..."
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Cited by 86 (8 self)
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Markov chain Monte Carlo (MCMC) sampling strategies can be used to simulate hidden Markov model (HMM) parameters from their posterior distribution given observed data. Some MCMC methods (for computing likelihood, conditional probabilities of hidden states, and the most likely sequence of states) used in practice can be improved by incorporating established recursive algorithms. The most important is a set of forwardbackward recursions calculating conditional distributions of the hidden states given observed data and model parameters. We show how to use the recursive algorithms in an MCMC context and demonstrate mathematical and empirical results showing a Gibbs sampler using the forwardbackward recursions mixes more rapidly than another sampler often used for HMM's. We introduce an augmented variables technique for obtaining unique state labels in HMM's and finite mixture models. We show how recursive computing allows statistically efficient use of MCMC output when estimating the hidden states. We directly calculate the posterior distribution of the hidden chain's state space size by MCMC, circumventing asymptotic arguments underlying the Bayesian information criterion, which is shown to be inappropriate for a frequently analyzed data set in the HMM literature. The use of loglikelihood for assessing MCMC convergence is illustrated, and posterior predictive checks are used to investigate application specific questions of model adequacy.
The practical implementation of Bayesian model selection
 Institute of Mathematical Statistics
, 2001
"... In principle, the Bayesian approach to model selection is straightforward. Prior probability distributions are used to describe the uncertainty surrounding all unknowns. After observing the data, the posterior distribution provides a coherent post data summary of the remaining uncertainty which is r ..."
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Cited by 85 (3 self)
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In principle, the Bayesian approach to model selection is straightforward. Prior probability distributions are used to describe the uncertainty surrounding all unknowns. After observing the data, the posterior distribution provides a coherent post data summary of the remaining uncertainty which is relevant for model selection. However, the practical implementation of this approach often requires carefully tailored priors and novel posterior calculation methods. In this article, we illustrate some of the fundamental practical issues that arise for two different model selection problems: the variable selection problem for the linear model and the CART model selection problem.
Modelling and interpretation of architecture from several images
"... The modelling of 3dimensional (3D) environments has become a requirement for many applications in engineering design, virtual reality, visualisation and entertainment. However the scale and complexity demanded from such models has risen to the point where the acquisition of 3D models can require a ..."
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Cited by 83 (6 self)
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The modelling of 3dimensional (3D) environments has become a requirement for many applications in engineering design, virtual reality, visualisation and entertainment. However the scale and complexity demanded from such models has risen to the point where the acquisition of 3D models can require a vast amount of specialist time and equipment. Because of this much research has been undertaken in the computer vision community into automating all or part of the process of acquiring a 3D model from a sequence of images. This thesis focuses specifically on the automatic acquisition of architectural models from short image sequences. An architectural model is defined as a set of planes corresponding to walls which contain a variety of labelled primitives such as doors and windows. As well as a label defining its type, each primitive contains parameters defining its shape and texture. The key advantage of this representation is that the model defines not only geometry and texture, but also an interpretation of the scene. This is crucial as it enables reasoning about the scene; for instance, structure and texture can be inferred in areas of the model which are unseen in any
Modelling heterogeneity with and without the Dirichlet process
, 2001
"... We investigate the relationships between Dirichlet process (DP) based models and allocation models for a variable number of components, based on exchangeable distributions. It is shown that the DP partition distribution is a limiting case of a Dirichlet± multinomial allocation model. Comparisons of ..."
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Cited by 68 (3 self)
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We investigate the relationships between Dirichlet process (DP) based models and allocation models for a variable number of components, based on exchangeable distributions. It is shown that the DP partition distribution is a limiting case of a Dirichlet± multinomial allocation model. Comparisons of posterior performance of DP and allocation models are made in the Bayesian paradigm and illustrated in the context of univariate mixture models. It is shown in particular that the unbalancedness of the allocation distribution, present in the prior DP model, persists a posteriori. Exploiting the model connections, a new MCMC sampler for general DP based models is introduced, which uses split/merge moves in a reversible jump framework. Performance of this new sampler relative to that of some traditional samplers for DP processes is then explored.
Decomposable Graphical Gaussian Model Determination
, 1999
"... We propose a methodology for Bayesian model determination in decomposable graphical gaussian models. To achieve this aim we consider a hyper inverse Wishart prior distribution on the concentration matrix for each given graph. To ensure compatibility across models, such prior distributions are obt ..."
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Cited by 64 (12 self)
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We propose a methodology for Bayesian model determination in decomposable graphical gaussian models. To achieve this aim we consider a hyper inverse Wishart prior distribution on the concentration matrix for each given graph. To ensure compatibility across models, such prior distributions are obtained by marginalisation from the prior conditional on the complete graph. We explore alternative structures for the hyperparameters of the latter, and their consequences for the model. Model determination is carried out by implementing a reversible jump MCMC sampler. In particular, the dimensionchanging move we propose involves adding or dropping an edge from the graph. We characterise the set of moves which preserve the decomposability of the graph, giving a fast algorithm for maintaining the junction tree representation of the graph at each sweep. As state variable, we propose to use the incomplete variancecovariance matrix, containing only the elements for which the correspondi...