Natural immune systems protect animals from dangerous foreign pathogens, including bacteria, viruses, parasites, and toxins. Their role in the body is analogous to that of computer security systems in computing. Although there are many differences between living organisms and computer systems, this article argues that the similarities are compelling and could point the way to improved computer security. Improvements can be achieved by designing computer immune systems that have some of the important properties illustrated by natural immune systems. These include multi-layered protection, highly distributed detection and memory systems, diversity of detection ability across individuals, inexact matching strategies, and sensitivity to most new foreign patterns. We first give an overview of how the immune system relates to computer security. We then illustrate these ideas with two examples.

The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature. This paper presents an artificial immune system (AIS) that exploits some of these characteristics and is applied to the task of film recommendation by collaborative filtering (CF). Natural evolution and in particular the immune system have not been designed for classical optimisation. However, for this problem, we are not interested in finding a single optimum. Rather we intend to identify a sub-set of good matches on which recommendations can be based. It is our hypothesis that an AIS built on two central aspects of the biological immune system will be an ideal candidate to achieve this: Antigen - antibody interaction for matching and antibody - antibody interaction for diversity. Computational results are presented in support of this conjecture and compared to those found by other CF techniques.

corresponding author Abstract-The immune system is a complex biological system with a highly distributed, adaptive and selforganising nature. This paper presents an Artificial Immune System (AIS) that exploits some of these characteristics and is applied to the task of film recommendation by Collaborative Filtering (CF). Natural evolution and in particular the immune system have not been designed for classical optimisation. However, for this problem, we are not interested in finding a single optimum. Rather we intend to identify a sub-set of good matches on which recommendations can be based. It is our hypothesis that an AIS built on two central aspects of the biological immune system will be an ideal candidate to achieve this: Antigen-antibody interaction for matching and idiotypic antibody-antibody interaction for diversity. Computational results are presented in support of this conjecture and compared to those found by other CF techniques. 1

Artificial Immune Systems have been used successfully to build recommender systems for film databases. In this research, an attempt is made to extend this idea to web site recommendation. A collection of more than 1000 individuals ’ web profiles (alternatively called preferences / favourites / bookmarks file) will be used. URLs will be classified using the DMOZ (Directory Mozilla) database of the Open Directory Project as our ontology. This will then be used as the data for the Artificial Immune Systems rather than the actual addresses. The first attempt will involve using a simple classification code number coupled with the number of pages within that classification code. However, this implementation does not make use of the hierarchical tree-like structure of DMOZ. Consideration will then be given to the construction of a similarity measure for web profiles that makes use of this hierarchical information to build a better-informed Artificial Immune System. 1

Abstract-The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature. This paper presents an artificial immune system (AIS) that exploits some of these characteristics and is applied to the task of film recommendation by collaborative filtering (CF). Natural evolution and in particular the immune system have not been designed for classical optimisation. However, for this problem, we are not intereste d in finding a single optimum. Rather we intend to identify a sub-set of good matches on which recommendations can be based. It is our hypothesis that an AIS built on two central aspects of the biological immune system will be an ideal candidate to achieve this: Antigen- antibody interaction for matching and antibody- antibody interaction for diversity. Computational results are presented in support of this conjecture and compared to those found by other CF techniques. I.

It has previously been shown that a recommender based on immune system idiotypic principles can outperform one based on correlation alone. This paper reports the results of work in progress, where we undertake some investigations into the nature of this beneficial effect. The initial findings are that the immune system recommender tends to produce different neighbourhoods, and that the superior performance of this recommender is due partly to the different neighbourhoods, and partly to the way that the idiotypic effect is used to weight each neighbour's recommendations.

The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature. This paper presents an artificial immune system (AIS) that exploits some of these characteristics and is applied to the task of film recommendation by collaborative filtering (CF). Natural evolution and in particular the immune system have not been designed for classical optimisation. However, for this problem, we are not interested in finding a single optimum. Rather we intend to identify a sub-set of good matches on which recommendations can be based. It is our hypothesis that an AIS built on two central aspects of the biological immune system will be an ideal candidate to achieve this: Antigen - antibody interaction for matching and antibody - antibody interaction for diversity. Computational results are presented in support of this conjecture and compared to those found by other CF techniques.

The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature.

Abstract. The paper presents a computer experiment inspired on the immune metaphor and based on the work of Farmer, Packard, and Perelson [FPP86]. We develop a model influenced by the way the immune system works that is well-suited to address a class of NP-hard problems. We discuss the results obtained when applying the model to an artificial vision problem denoted the museum problem, where artificial agents successfully accomplish a surveillance assignment to protect the pieces of an art exhibition from bad behaved visitors. 1

Modelling vaccination schedules for a cancer immunoprevention vaccine