. This paper gives an overview of scale-space and image enhancement techniques which are based on parabolic partial differential equations in divergence form. In the nonlinear setting this filter class allows to integrate a-priori knowledge into the evolution. We sketch basic ideas behind the different filter models, discuss their theoretical foundations and scale-space properties, discrete aspects, suitable algorithms, generalizations, and applications. 1 Introduction During the last decade nonlinear diffusion filters have become a powerful and well-founded tool in multiscale image analysis. These models allow to include a-priori knowledge into the scale-space evolution, and they lead to an image simplification which simultaneously preserves or even enhances semantically important information such as edges, lines, or flow-like structures. Many papers have appeared proposing different models, investigating their theoretical foundations, and describing interesting applications. For a n...

The completion of interrupted lines or the enhancement of flow-like structures is a challenging task in computer vision, human vision, and image processing. We address this problem by presenting a multiscale method in which a nonlinear diffusion filter is steered by the so-called interest operator (second-moment matrix, structure tensor). An m-dimensional formulation of this method is analysed with respect to its well-posedness and scale-space properties. An efficient scheme is presented which uses a stabilization by a semi-implicit additive operator splitting (AOS), and the scale-space behaviour of this method is illustrated by applying it to both 2-D and 3-D images.

Detection of tubular structures in 3D images is an important issue for vascular detection in medical imaging. We present in this paper a new approach for centerline detection and reconstruction of 3D tubular structures. Several models of vessels are introduced for estimating the sensivity of the image second order derivatives according to elliptical cross-section, to curvature of the axis, or to partial volume e#ects. Our approach uses a multiscale analysis for extracting vessels of di#erent sizes according to the scale. For a given model of vessel, we derive an analytic expression of the relationship between the radius of the structure and the scale at which it is detected. The algorithm gives both centerline extraction and radius estimation of the vessels allowing their reconstruction. The method has been tested on both synthetic and real images, with encouraging results. This work was done in collaboration with GEMS .

Three-dimensional rotational angiography (3DRA) is a new and promising technique for obtaining high-resolution isotropic 3D images of vascular structures. However, due to the relatively high noise level and the presence of other background structures in clinical 3DRA images, noise reduction is inevitable. In this paper, we evaluate a number of linear and nonlinear diffusion techniques for this purpose. Specifically, we analyze the effects of these techniques on the thresholdbased visualization and quantification of vascular anomalies in 3DRA images. The results of invitro experiments indicate that edge-enhancing anisotropic diffusion filtering is most suitable: the increase in the user-dependency of visualizations and quantifications is considerably less with this technique compared to linear filtering techniques, and it is better at reducing noise near edges than isotropic nonlinear diffusion. However, in view of the memory and computation-time requirements of this technique, the latter scheme may be considered a useful alternative.