The purpose of this paper is to set up a theory of generalized operads and multicategories and to use it as a language in which to propose a definition of weak n-category. Included is a full explanation of why the proposed definition of n-category is a reasonable one, and of what happens when n <= 2. Generalized operads and multicategories play other parts in higher-dimensional algebra too, some of which are outlined here: for instance, they can be used to simplify the opetopic approach to n-categories expounded by Baez, Dolan and others, and are a natural language in which to discuss enrichment of categorical structures.

We give an elementary and direct combinatorial definition of opetopes in terms of trees, well-suited for graphical manipulation (e.g. drawings of opetopes of any dimension and basic operations like sources, target, and composition); a substantial part of the paper is constituted by drawings and example computations. To relate our definition to the classical definition, we recast the Baez-Dolan slice construction for operads in terms of polynomial monads: our opetopes appear naturally as types for polynomial monads obtained by iterating the Baez-Dolan construction, starting with the trivial monad. Finally we observe a suspension operation for opetopes, and define a notion of stable opetopes. Stable opetopes form a least fixpoint for the Baez-Dolan construction. The calculus of opetopes is also well-suited for machine implementation: in an appendix we show how to represent opetopes in XML, and manipulate them with simple Tcl scripts.

We give an explicit construction of the category Opetope of opetopes. We prove that the category of opetopic sets is equivalent to the category of presheaves over Opetope.

We begin with a chronology tracing the rise of symmetry concepts in physics, starting with groups and their role in relativity, and leading up to more sophisticated concepts from n-category theory, which manifest themselves in Feynman diagrams and their higherdimensional generalizations: strings, membranes and spin foams.

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