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Regression Shrinkage and Selection Via the Lasso
 Journal of the Royal Statistical Society, Series B
, 1994
"... We propose a new method for estimation in linear models. The "lasso" minimizes the residual sum of squares subject to the sum of the absolute value of the coefficients being less than a constant. Because of the nature of this constraint it tends to produce some coefficients that are exactl ..."
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Cited by 2066 (40 self)
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We propose a new method for estimation in linear models. The "lasso" minimizes the residual sum of squares subject to the sum of the absolute value of the coefficients being less than a constant. Because of the nature of this constraint it tends to produce some coefficients that are exactly zero and hence gives interpretable models. Our simulation studies suggest that the lasso enjoys some of the favourable properties of both subset selection and ridge regression. It produces interpretable models like subset selection and exhibits the stability of ridge regression. There is also an interesting relationship with recent work in adaptive function estimation by Donoho and Johnstone. The lasso idea is quite general and can be applied in a variety of statistical models: extensions to generalized regression models and treebased models are briefly described. Keywords: regression, subset selection, shrinkage, quadratic programming. 1 Introduction Consider the usual regression situation: we h...
Additive Logistic Regression: a Statistical View of Boosting
 Annals of Statistics
, 1998
"... Boosting (Freund & Schapire 1996, Schapire & Singer 1998) is one of the most important recent developments in classification methodology. The performance of many classification algorithms can often be dramatically improved by sequentially applying them to reweighted versions of the input dat ..."
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Cited by 1320 (21 self)
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Boosting (Freund & Schapire 1996, Schapire & Singer 1998) is one of the most important recent developments in classification methodology. The performance of many classification algorithms can often be dramatically improved by sequentially applying them to reweighted versions of the input data, and taking a weighted majority vote of the sequence of classifiers thereby produced. We show that this seemingly mysterious phenomenon can be understood in terms of well known statistical principles, namely additive modeling and maximum likelihood. For the twoclass problem, boosting can be viewed as an approximation to additive modeling on the logistic scale using maximum Bernoulli likelihood as a criterion. We develop more direct approximations and show that they exhibit nearly identical results to boosting. Direct multiclass generalizations based on multinomial likelihood are derived that exhibit performance comparable to other recently proposed multiclass generalizations of boosting in most...
Hierarchical mixtures of experts and the EM algorithm
 Neural Computation
, 1994
"... We present a treestructured architecture for supervised learning. The statistical model underlying the architecture is a hierarchical mixture model in which both the mixture coefficients and the mixture components are generalized linear models (GLIM’s). Learning is treated as a maximum likelihood ..."
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Cited by 764 (20 self)
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We present a treestructured architecture for supervised learning. The statistical model underlying the architecture is a hierarchical mixture model in which both the mixture coefficients and the mixture components are generalized linear models (GLIM’s). Learning is treated as a maximum likelihood problem; in particular, we present an ExpectationMaximization (EM) algorithm for adjusting the parameters of the architecture. We also develop an online learning algorithm in which the parameters are updated incrementally. Comparative simulation results are presented in the robot dynamics domain. 1
Greedy Function Approximation: A Gradient Boosting Machine
 Annals of Statistics
, 2000
"... Function approximation is viewed from the perspective of numerical optimization in function space, rather than parameter space. A connection is made between stagewise additive expansions and steepest{descent minimization. A general gradient{descent \boosting" paradigm is developed for additi ..."
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Cited by 623 (12 self)
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Function approximation is viewed from the perspective of numerical optimization in function space, rather than parameter space. A connection is made between stagewise additive expansions and steepest{descent minimization. A general gradient{descent \boosting" paradigm is developed for additive expansions based on any tting criterion. Specic algorithms are presented for least{squares, least{absolute{deviation, and Huber{M loss functions for regression, and multi{class logistic likelihood for classication. Special enhancements are derived for the particular case where the individual additive components are regression trees, and tools for interpreting such \TreeBoost" models are presented. Gradient boosting of regression trees produces competitive, highly robust, interpretable procedures for both regression and classication, especially appropriate for mining less than clean data. Connections between this approach and the boosting methods of Freund and Shapire 1996, and Frie...
Estimating Continuous Distributions in Bayesian Classifiers
 In Proceedings of the Eleventh Conference on Uncertainty in Artificial Intelligence
, 1995
"... When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated by a single Gaussian. In this paper we abandon the normality ..."
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Cited by 343 (2 self)
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When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated by a single Gaussian. In this paper we abandon the normality assumption and instead use statistical methods for nonparametric density estimation. For a naive Bayesian classifier, we present experimental results on a variety of natural and artificial domains, comparing two methods of density estimation: assuming normality and modeling each conditional distribution with a single Gaussian; and using nonparametric kernel density estimation. We observe large reductions in error on several natural and artificial data sets, which suggests that kernel estimation is a useful tool for learning Bayesian models. In Proceedings of the Eleventh Conference on Uncertainty in Artificial Intelligence, Morgan Kaufmann Publishers, San Mateo, 1995 1 Introduction In rec...
Regularization Theory and Neural Networks Architectures
 Neural Computation
, 1995
"... We had previously shown that regularization principles lead to approximation schemes which are equivalent to networks with one layer of hidden units, called Regularization Networks. In particular, standard smoothness functionals lead to a subclass of regularization networks, the well known Radial Ba ..."
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Cited by 332 (31 self)
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We had previously shown that regularization principles lead to approximation schemes which are equivalent to networks with one layer of hidden units, called Regularization Networks. In particular, standard smoothness functionals lead to a subclass of regularization networks, the well known Radial Basis Functions approximation schemes. This paper shows that regularization networks encompass a much broader range of approximation schemes, including many of the popular general additive models and some of the neural networks. In particular, we introduce new classes of smoothness functionals that lead to different classes of basis functions. Additive splines as well as some tensor product splines can be obtained from appropriate classes of smoothness functionals. Furthermore, the same generalization that extends Radial Basis Functions (RBF) to Hyper Basis Functions (HBF) also leads from additive models to ridge approximation models, containing as special cases Breiman's hinge functions, som...
Classification by pairwise coupling
, 1998
"... We discuss a strategy for polychotomous classification that involves estimating class probabilities for each pair of classes, and then coupling the estimates together. The coupling model is similar to the BradleyTerry method for paired comparisons. We study the nature of the class probability estim ..."
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Cited by 295 (0 self)
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We discuss a strategy for polychotomous classification that involves estimating class probabilities for each pair of classes, and then coupling the estimates together. The coupling model is similar to the BradleyTerry method for paired comparisons. We study the nature of the class probability estimates that arise, and examine the performance of the procedure in real and simulated datasets. Classifiers used include linear discriminants, nearest neighbors, and the support vector machine.
Regularization networks and support vector machines
 Advances in Computational Mathematics
, 2000
"... Regularization Networks and Support Vector Machines are techniques for solving certain problems of learning from examples – in particular the regression problem of approximating a multivariate function from sparse data. Radial Basis Functions, for example, are a special case of both regularization a ..."
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Cited by 288 (34 self)
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Regularization Networks and Support Vector Machines are techniques for solving certain problems of learning from examples – in particular the regression problem of approximating a multivariate function from sparse data. Radial Basis Functions, for example, are a special case of both regularization and Support Vector Machines. We review both formulations in the context of Vapnik’s theory of statistical learning which provides a general foundation for the learning problem, combining functional analysis and statistics. The emphasis is on regression: classification is treated as a special case.
Analysis of variance for gene expression microarray data
 Journal of Computational Biology
, 2000
"... Spotted cDNA microarrays are emerging as a powerful and costeffective tool for largescale analysis of gene expression. Microarrays can be used to measure the relative quantities of speci � c mRNAs in two or more tissue samples for thousands of genes simultaneously. While the power of this technolog ..."
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Cited by 267 (5 self)
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Spotted cDNA microarrays are emerging as a powerful and costeffective tool for largescale analysis of gene expression. Microarrays can be used to measure the relative quantities of speci � c mRNAs in two or more tissue samples for thousands of genes simultaneously. While the power of this technology has been recognized, many open questions remain about appropriate analysis of microarray data. One question is how to make valid estimates of the relative expression for genes that are not biased by ancillary sources of variation. Recognizing that there is inherent “noise ” in microarray data, how does one estimate the error variation associated with an estimated change in expression, i.e., how does one construct the error bars? We demonstrate that ANOVA methods can be used to normalize microarray data and provide estimates of changes in gene expression that are corrected for potential confounding effects. This approach establishes a framework for the general analysis and interpretation of microarray data. Key words: Gene expression microarray, differential expression, analysis of variance, bootstrap.
Independent Factor Analysis
 Neural Computation
, 1999
"... We introduce the independent factor analysis (IFA) method for recovering independent hidden sources from their observed mixtures. IFA generalizes and unifies ordinary factor analysis (FA), principal component analysis (PCA), and independent component analysis (ICA), and can handle not only square no ..."
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Cited by 238 (9 self)
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We introduce the independent factor analysis (IFA) method for recovering independent hidden sources from their observed mixtures. IFA generalizes and unifies ordinary factor analysis (FA), principal component analysis (PCA), and independent component analysis (ICA), and can handle not only square noiseless mixing, but also the general case where the number of mixtures differs from the number of sources and the data are noisy. IFA is a twostep procedure. In the first step, the source densities, mixing matrix and noise covariance are estimated from the observed data by maximum likelihood. For this purpose we present an expectationmaximization (EM) algorithm, which performs unsupervised learning of an associated probabilistic model of the mixing situation. Each source in our model is described by a mixture of Gaussians, thus all the probabilistic calculations can be performed analytically. In the second step, the sources are reconstructed from the observed data by an optimal nonlinear ...