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Results 1 - 10
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4,510
Reverse Transcriptase
"... The emergence of HIV-1 drug resistance remains a major obstacle in antiviral therapy. M184I/V and E138K are signature muta-tions of clinical relevance in HIV-1 reverse transcriptase (RT) for the nucleoside reverse transcriptase inhibitors (NRTIs) lami-vudine (3TC) and emtricitabine (FTC) and the sec ..."
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The emergence of HIV-1 drug resistance remains a major obstacle in antiviral therapy. M184I/V and E138K are signature muta-tions of clinical relevance in HIV-1 reverse transcriptase (RT) for the nucleoside reverse transcriptase inhibitors (NRTIs) lami-vudine (3TC) and emtricitabine (FTC
Reverse Transcriptase
, 1993
"... transcriptase. immunodeficiency virus type 1 reverse by a mutation in codon 65 of the human Resistance to 2',3'-dideoxycytidine conferred ..."
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transcriptase. immunodeficiency virus type 1 reverse by a mutation in codon 65 of the human Resistance to 2',3'-dideoxycytidine conferred
Reverse Transcriptase
, 2001
"... This article cites 64 articles, 41 of which can be accessed free ..."
Reverse Transcriptase
, 2002
"... This article cites 32 articles, 17 of which can be accessed free ..."
Reverse Transcriptase
, 2000
"... This article cites 24 articles, 16 of which can be accessed free ..."
Type 1 Reverse Transcriptase
, 1992
"... A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl sulfone (NPPS), completely protected human CEM-SS l ..."
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-SS lymphoblastoid cells from the cytopathic effects of HIV-1 in cell culture at 1 to 5 pM concentrations. HIV-1 replication, as assessed by the production of infectious virions, viral p24 antigen, and virion reverse transcriptase (RT), was inhibited by NPPS at similar concentrations. There was no evidence of direct
HIV-1 reverse transcriptase inhibitor
, 2012
"... HIV-1 (Human immunodeficiency virus type 1) is a member of retrovirus family that could infect human and causing AIDS disease. AIDS epidemic is one of most destructive diseases in modern era. There were more than 33 million people infected by HIV until 2010. Various studies have been widely employed ..."
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employed to design drugs that target the essential enzymes of HIV-1 that is, reverse transcriptase, protease and integrase. In this study, in silico virtual screening approach is used to find lead molecules from the library or database of natural compounds as HIV-1 reverse transcriptase inhibitor. Virtual
In Situ Reverse Transcriptase PCR
, 1996
"... transcriptase PCR. trigeminal ganglia by in situ reverse latency-associated transcript expression in Detection of herpes simplex virus type 1 ..."
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transcriptase PCR. trigeminal ganglia by in situ reverse latency-associated transcript expression in Detection of herpes simplex virus type 1
Results 1 - 10
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