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Modelling of protein interaction networks

by Alexei Vazquez, Ro Flammini, Amos Maritan, Ro Vespignani , 2001
"... We introduce a graph generating model aimed at representing the evolution of protein interaction networks. The model is based on the hypotesis of evolution by duplications and divergence of the genes which produce proteins. The obtained graphs shows multifractal properties recovering the absence of ..."
Abstract - Cited by 73 (0 self) - Add to MetaCart
We introduce a graph generating model aimed at representing the evolution of protein interaction networks. The model is based on the hypotesis of evolution by duplications and divergence of the genes which produce proteins. The obtained graphs shows multifractal properties recovering the absence

Recent advances in clustering methods for protein interaction networks

by Jianxin Wang, Min Li, Youping Deng, Yi Pan, Jianxin Wang, Min Li, Youping Deng, Yi Pan - BMC genomics, 11(Suppl 3):S10 , 2010
"... Recent advances in clustering methods for protein interaction networks ..."
Abstract - Cited by 20 (0 self) - Add to MetaCart
Recent advances in clustering methods for protein interaction networks

Enhancing the functional content of protein interaction networks

by Gaurav P, Sahil Manocha, Gowtham Atluri, Vipin Kumar, Gaurav P, Sahil Manocha, Gowtham Atluri, Vipin Kumar
"... Enhancing the functional content of protein interaction networks ..."
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Enhancing the functional content of protein interaction networks

Evolutionary rate in the protein interaction network

by Hunter B. Fraser, Aaron E. Hirsh, Lars M. Steinmetz, Curt Scharfe, Marcus W. Feldman - Science
"... High-throughput screens have begun to reveal the protein interaction network that underpins most cellular functions in the yeast Saccharomyces cerevisiae. How the organization of this network affects the evolution of the proteins that compose it is a fundamental question in molecular evolution. We s ..."
Abstract - Cited by 98 (0 self) - Add to MetaCart
High-throughput screens have begun to reveal the protein interaction network that underpins most cellular functions in the yeast Saccharomyces cerevisiae. How the organization of this network affects the evolution of the proteins that compose it is a fundamental question in molecular evolution. We

Functional and topological characterization of protein interaction networks

by Soon-hyung Yook, Zoltán N. Oltvai, Albert-lászló Barabási - Proteomics , 2004
"... The elucidation of the cell’s large-scale organization is a primary challenge for post-genomic biology, and understanding the structure of protein interaction networks offers an important starting point for such studies. We compare four available databases that approximate the protein interaction ne ..."
Abstract - Cited by 95 (3 self) - Add to MetaCart
The elucidation of the cell’s large-scale organization is a primary challenge for post-genomic biology, and understanding the structure of protein interaction networks offers an important starting point for such studies. We compare four available databases that approximate the protein interaction

Conservation of protein interaction network in evolution

by Jong Park, Dan Bolser - Genome Informatics , 2001
"... A functional analysis of protein fold interaction suggested that structural fold familieshave gradually acquired more diverse interacting partners while maintaining central biochemical interactions and functions. This means thatthe protein interaction network (map) maintains its robust architecture ..."
Abstract - Cited by 12 (1 self) - Add to MetaCart
A functional analysis of protein fold interaction suggested that structural fold familieshave gradually acquired more diverse interacting partners while maintaining central biochemical interactions and functions. This means thatthe protein interaction network (map) maintains its robust architecture

Querying protein-protein interaction networks

by Guillaume Blin, Florian Sikora - in Proceedings of the 5th International Symposium on Bioinformatics Research and Applications , 2009
"... Abstract. Recent techniques increase the amount of our knowledge of interactions between proteins. To filter, interpret and organize this data, many authors have provided tools for querying patterns in the shape of paths or trees in Protein-Protein Interaction networks. In this paper, we propose an ..."
Abstract - Cited by 5 (3 self) - Add to MetaCart
Abstract. Recent techniques increase the amount of our knowledge of interactions between proteins. To filter, interpret and organize this data, many authors have provided tools for querying patterns in the shape of paths or trees in Protein-Protein Interaction networks. In this paper, we propose

the protein–protein interaction network

by Hongchao Lu, Xiaopeng Zhu, Haifeng Liu, Geir Skogerbø, Jingfen Zhang, Yong Zhang, Lun Cai, Yi Zhao, Shiwei Sun, Jingyi Xu, Dongbo Bu, Runsheng Chen , 2004
"... The interactome as a tree—an attempt to visualize ..."
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The interactome as a tree—an attempt to visualize

protein-protein interaction network

by Feng Xu, Chen Zhao, Yuhua Li, Jiang Li, Youping Deng, Tieliu Shi
"... Exploring virus relationships based on virus-host ..."
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Exploring virus relationships based on virus-host

in protein–protein interaction networks

by Iaroslav Ispolatov, Anton Yuryev, Ilya Mazo, Sergei Maslov , 2005
"... Binding properties and evolution of homodimers ..."
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Binding properties and evolution of homodimers
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