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Abnormalities of fixation, saccade and pursuit in posterior cortical atrophy

by F. Slattery, Natalie S. Ryan, Jonathan M. Schott, Sebastian J. Crutch
"... See Antoniades and Kennard (doi:10.1093/brain/awv124) for a scientific commentary on this article. The clinico-neuroradiological syndrome posterior cortical atrophy is the cardinal ‘visual dementia ’ and most common atypical Alzheimer’s disease phenotype, offering insights into mechanisms underlying ..."
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See Antoniades and Kennard (doi:10.1093/brain/awv124) for a scientific commentary on this article. The clinico-neuroradiological syndrome posterior cortical atrophy is the cardinal ‘visual dementia ’ and most common atypical Alzheimer’s disease phenotype, offering insights into mechanisms

Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy

by unknown authors
"... Posterior cortical atrophy (PCA) represents a degenera-tive disorder characterized by the development of higher-order visual deficit.1 PCA may result from heterogeneous pathologies that make up tauopathies. An increasing number of mutations in the tau gene (microtubule-associated protein tau [MAPT]) ..."
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Posterior cortical atrophy (PCA) represents a degenera-tive disorder characterized by the development of higher-order visual deficit.1 PCA may result from heterogeneous pathologies that make up tauopathies. An increasing number of mutations in the tau gene (microtubule-associated protein tau [MAPT

The evolution of alexia in two cases of posterior cortical atrophy

by Eleonora Catricalà , Pasquale A Della Rosa , Paola Ortelli , Valeria Ginex , Alessandra Marcone , Daniela Perani , Stefano F Cappa , 2011
"... Abstract. Posterior cortical atrophy (PCA) is an uncommon presentation of Alzheimer's disease (AD), characterised by prevalent anatomo-functional involvement of posterior cortical areas. Accordingly, the main clinical features at onset are disorders of high-order visual processing, such as ale ..."
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Abstract. Posterior cortical atrophy (PCA) is an uncommon presentation of Alzheimer's disease (AD), characterised by prevalent anatomo-functional involvement of posterior cortical areas. Accordingly, the main clinical features at onset are disorders of high-order visual processing

ORIGINAL COMMUNICATION Logopenic syndrome in posterior cortical atrophy

by Eloi Magnin, Geraldine Sylvestre, Flora Lenoir, Elfried Dariel, Louise Bonnet, Gilles Chopard, Gregory Tio, Julie Hidalgo, Sabrina Ferreira, Catherine Mertz, Mikael Binetruy, Ludivine Chamard, Sophie Haffen, El Lucien Rumbach
"... Abstract Few language disorders have been reported in posterior cortical atrophy (PCA). Furthermore, no study has focused on screening for them and described these language deficits. The goal of this work was to describe linguistic examination of PCA patients and the impact of language disorders on ..."
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Abstract Few language disorders have been reported in posterior cortical atrophy (PCA). Furthermore, no study has focused on screening for them and described these language deficits. The goal of this work was to describe linguistic examination of PCA patients and the impact of language disorders

REVIEWARTICLE Posterior cortical atrophy and Alzheimer’s disease:

by Jorge Alves, José Miguel Soares, Adriana Sampaio, Óscar F. Gonçalves
"... a meta-analytic review of neuropsychological and brain morphometry studies ..."
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a meta-analytic review of neuropsychological and brain morphometry studies

Shining a light on posterior cortical atrophy. Alzheimers Dement

by Sebastian J Crutch , Jonathan M Schott , Gil D Rabinovici , Bradley F Boeve , Stefano F Cappa , Bradford C Dickerson , Bruno Dubois , Neill R Graff-Radford , Pierre Krolak-Salmon , Manja Lehmann , Mario F Mendez , Yolande Pijnenburg , Natalie S Ryan , Philip Scheltens , Tim Shakespeare , David F Tang-Wai , Wiesje M Van Der Flier , Lisa Bain , Maria C Carrillo , Nick C Fox
"... Abstract Posterior cortical atrophy (PCA) is a clinicoradiologic syndrome characterized by progressive decline in visual processing skills, relatively intact memory and language in the early stages, and atrophy of posterior brain regions. Misdiagnosis of PCA is common, owing not only to its relativ ..."
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Abstract Posterior cortical atrophy (PCA) is a clinicoradiologic syndrome characterized by progressive decline in visual processing skills, relatively intact memory and language in the early stages, and atrophy of posterior brain regions. Misdiagnosis of PCA is common, owing not only to its

RESEARCH ARTICLE Open Access Visual neglect in posterior cortical atrophy

by Katia Andrade, Dalila Samri, Marie Sarazin, Leonardo C De Souza, Laurent Cohen, Michel Thiebaut De Schotten, Bruno Dubois, Paolo Bartolomeo
"... Background: In posterior cortical atrophy (PCA), there is a progressive impairment of high-level visual functions and parietal damage, which might predict the occurrence of visual neglect. However, neglect may pass undetected if not assessed with specific tests, and might therefore be underestimated ..."
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Background: In posterior cortical atrophy (PCA), there is a progressive impairment of high-level visual functions and parietal damage, which might predict the occurrence of visual neglect. However, neglect may pass undetected if not assessed with specific tests, and might therefore

ORIGINAL COMMUNICATION Clinical, FDG and amyloid PET imaging in posterior cortical atrophy

by unknown authors
"... Abstract The purpose of this study was to identify the clinical, [18F]-fluorodeoxyglucose positron emission to-mography (FDG-PET) and amyloid-PET findings in a large cohort of posterior cortical atrophy (PCA) patients, to ex-amine the neural correlates of the classic features of PCA, and to better u ..."
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Abstract The purpose of this study was to identify the clinical, [18F]-fluorodeoxyglucose positron emission to-mography (FDG-PET) and amyloid-PET findings in a large cohort of posterior cortical atrophy (PCA) patients, to ex-amine the neural correlates of the classic features of PCA, and to better

Case Reports The Progression of Posterior Cortical Atrophy to Corticobasal Syndrome: Lumping or Splitting Neurodegenerative Diseases?

by Maurizio Giorelli, Nunzia Aless, Ra Losignore, Junia Bagnoli, Pasquale Difazio, Giovanni Bosco Zimatore
"... Background: Posterior cortical atrophy is a clinical syndrome that is characterized by the progressive loss of visuospatial integration and is associated with neurodegenerative conditions. Case Report: We describe a 60-year-old female with simultanagnosia, oculomotor apraxia, and optic ataxia for wh ..."
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Background: Posterior cortical atrophy is a clinical syndrome that is characterized by the progressive loss of visuospatial integration and is associated with neurodegenerative conditions. Case Report: We describe a 60-year-old female with simultanagnosia, oculomotor apraxia, and optic ataxia

Short Communication Pronounced Impairment of Everyday Skills and Self-Care in Posterior Cortical Atrophy

by Timothy J. Shakespearea, Keir X. X. Yonga, David Foxeb, John Hodgesb, Sebastian J. Crutcha , 2014
"... Abstract. Posterior cortical atrophy (PCA) is a neurodegenerative syndrome characterized by progressive visual dysfunction and parietal, occipital, and occipitotemporal atrophy. The aim of this study was to compare the impact of PCA and typical Alzheimer’s disease (tAD) on everyday functional abilit ..."
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Abstract. Posterior cortical atrophy (PCA) is a neurodegenerative syndrome characterized by progressive visual dysfunction and parietal, occipital, and occipitotemporal atrophy. The aim of this study was to compare the impact of PCA and typical Alzheimer’s disease (tAD) on everyday functional
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