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The embryonic cell lineage of the nematode Caenorhabditis elegans

by J. E. Sulston, H. R. Horvitz - Dev. Biol , 1983
"... The number of nongonadal nuclei in the free-living soil nematode Caenorhabditis elegans increases from about 550 in the newly hatched larva to about 810 in the mature hermaphrodite and to about 970 in the mature male. The pattern of cell divisions which leads to this increase is essentially invarian ..."
Abstract - Cited by 540 (19 self) - Add to MetaCart
in living nematodes. Many of the cell lineages are involved in sexual maturation. At hatching, the hermaphrodite and male are almost identical morphologically; by the adult stage, gross anatomical differences are obvious. Some of these sexual differences arise from blast cells whose division patterns

Relations between the statistics of natural images and the response properties of cortical cells

by David J. Field - J. Opt. Soc. Am. A , 1987
"... The relative efficiency of any particular image-coding scheme should be defined only in relation to the class of images that the code is likely to encounter. To understand the representation of images by the mammalian visual system, it might therefore be useful to consider the statistics of images f ..."
Abstract - Cited by 831 (18 self) - Add to MetaCart
cells are well suited for coding the information in such images if the goal of the code is to convert higher-order redundancy (e.g., correlation between the intensities of neighboring pixels) into first-order redundancy (i.e., the response distribution of the coefficients). Such coding produces a

Comparison of discrimination methods for the classification of tumors using gene expression data

by Sandrine Dudoit, Jane Fridlyand, Terence P. Speed - JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION , 2002
"... A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel biotechnologies increasingly used in cancer research. By allowing the monitoring of expression levels in cells for thousand ..."
Abstract - Cited by 770 (6 self) - Add to MetaCart
A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel biotechnologies increasingly used in cancer research. By allowing the monitoring of expression levels in cells

The capacity of wireless networks

by Piyush Gupta, P. R. Kumar - IEEE TRANSACTIONS ON INFORMATION THEORY , 2000
"... When n identical randomly located nodes, each capable of transmitting at bits per second and using a fixed range, form a wireless network, the throughput @ A obtainable by each node for a randomly chosen destination is 2 bits per second under a noninterference protocol. If the nodes are optimally p ..."
Abstract - Cited by 3243 (42 self) - Add to MetaCart
When n identical randomly located nodes, each capable of transmitting at bits per second and using a fixed range, form a wireless network, the throughput @ A obtainable by each node for a randomly chosen destination is 2 bits per second under a noninterference protocol. If the nodes are optimally

The Large-Scale Organization of Metabolic Networks

by H. Jeong, B. Tombor, R. Albert, Z. N. Oltvai, A.-L. Barabási , 2000
"... In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular ..."
Abstract - Cited by 609 (7 self) - Add to MetaCart
In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular

Tandem repeats finder: a program to analyze DNA sequences

by Gary Benson , 1999
"... A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown to cause human disease, may play a variety of regulatory and evolutionary roles and are important laboratory and analytic tools. Extensive knowledge about pattern size, co ..."
Abstract - Cited by 961 (9 self) - Add to MetaCart
repeats by percent identity and frequency of indels between adjacent pattern copies and use statistically based recognition criteria. We demonstrate the algorithm's speed and its ability to detect tandem repeats that have undergone extensive mutational change by analyzing four sequences: the human

When Is "Nearest Neighbor" Meaningful?

by Kevin Beyer, Jonathan Goldstein, Raghu Ramakrishnan, Uri Shaft - In Int. Conf. on Database Theory , 1999
"... . We explore the effect of dimensionality on the "nearest neighbor " problem. We show that under a broad set of conditions (much broader than independent and identically distributed dimensions), as dimensionality increases, the distance to the nearest data point approaches the distance ..."
Abstract - Cited by 408 (2 self) - Add to MetaCart
. We explore the effect of dimensionality on the "nearest neighbor " problem. We show that under a broad set of conditions (much broader than independent and identically distributed dimensions), as dimensionality increases, the distance to the nearest data point approaches

The structure of the potassium channel: molecular basis of K+ conduction and selectivity

by Declan A. Doyle, João Morais Cabral, Richard A. Pfuetzner, Anling Kuo, Jacqueline M. Gulbis, Steven L. Cohen, Brian T. Chait, Roderick Mackinnon - Science , 1998
"... The potassium channel from Streptomyces lividans is an integral membrane protein with sequence similarity to all known K1 channels, particularly in the pore region. X-ray analysis with data to 3.2 angstroms reveals that four identical subunits create an inverted teepee, or cone, cradling the selecti ..."
Abstract - Cited by 460 (1 self) - Add to MetaCart
The potassium channel from Streptomyces lividans is an integral membrane protein with sequence similarity to all known K1 channels, particularly in the pore region. X-ray analysis with data to 3.2 angstroms reveals that four identical subunits create an inverted teepee, or cone, cradling

Inferotemporal Cortex and Object Vision.

by Keiji Tanaka - Annual Review of Neuroscience. , 1996
"... ABSTRACT Cells in area TE of the inferotemporal cortex of the monkey brain selectively respond to various moderately complex object features, and those that cluster in a columnar region that runs perpendicular to the cortical surface respond to similar features. Although cells within a column respo ..."
Abstract - Cited by 409 (4 self) - Add to MetaCart
respond to similar features, their selectivity is not necessarily identical. The data of optical imaging in 'E have suggested that the borders between neighboring columns are not discrete; a continuous mapping of complex feature space within a larger region contains several partially overlapped

Trickle: A Self-Regulating Algorithm for Code Propagation and Maintenance in Wireless Sensor Networks

by Philip Levis, Neil Patel, David Culler, Scott Shenker - In Proceedings of the First USENIX/ACM Symposium on Networked Systems Design and Implementation (NSDI , 2004
"... We present Trickle, an algorithm for propagating and maintaining code updates in wireless sensor networks. Borrowing techniques from the epidemic/gossip, scalable multicast, and wireless broadcast literature, Trickle uses a "polite gossip" policy, where motes periodically broadcast a code ..."
Abstract - Cited by 376 (9 self) - Add to MetaCart
summary to local neighbors but stay quiet if they have recently heard a summary identical to theirs. When a mote hears an older summary than its own, it broadcasts an update. Instead of flooding a network with packets, the algorithm controls the send rate so each mote hears a small trickle of packets
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