functions, their large-scale structure is essentially unknown. Here we present the first systematic comparative mathematical analysis of the metabolic networks of 43 organisms representing all three domains of life. We show that, despite significant variances in their individual constituents and pathways

the professional links between movie actors. 1 The complexity of numerous social, biological or communication systems is rooted in the rather interwoven web defined by the system’s components and their interactions. For example, cell functioning is guaranteed by a complex metabolic network, whose nodes

constitute its ‘metabolome’. Yet, unlike other functional genomics approaches, the unbiased simultaneous identification and quantification of plant metabolomes has been largely neglected. Until recently, most analyses were restricted to profiling selected classes of compounds, or to fingerprinting metabolic

placed in individual metabolism cages and they appeared lively, ate well, and kept their weight during the course of the experiment. D/et.--The diet consisted of Rockland Farm dried rat pellets ad libitum. This ration is composed as follows:--per ~c,a

Abstract. Metabolism provides a basis for using first principles of physics, chemistry, and biology to link the biology of individual organisms to the ecology of populations, communities, and ecosystems. Metabolic rate, the rate at which organisms take up, transform, and expend energy

level of binding preceded time development of recognizable necrosis by at least one to two hours. Pretreatment of mice with pimeno-barbital, piperonyl butoxide or cobaltous chloride, wisich cimanged time rate of metabolism of 3Hacetaminophen and altered time severity of imepatic necrosis, similarly

and metabolic parameters of red tilapia reared in floating

of both protein-protein interaction and metabolic networks is of a hierarchical scale-free nature 1,2 , characterized by an inverse relationship between the number of nodes and their connectivity (scale-free) and by a preferential interaction among highly connected genes, called hubs (hierarchical

of individual differences in behavioural inhibition in mice

SUMMARY 1. We studied the effect of isolation stress in 3-and 12-month-old rats individually housed in metabolic cages for 7 days. Urine (24 hr) was collected daily from one group of animals of each age. The other group was tested in an open field and on a hot plate on days 1 and 7. 2. Total