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A greedy algorithm for aligning DNA sequences

by Zheng Zhang, Scott Schwartz, Lukas Wagner, Webb Miller - J. COMPUT. BIOL , 2000
"... For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic programming approaches and yet produce an alignment that is guaranteed to be theoretically optimal. We introduce a new greedy a ..."
Abstract - Cited by 585 (16 self) - Add to MetaCart
For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic programming approaches and yet produce an alignment that is guaranteed to be theoretically optimal. We introduce a new greedy

Parallel Networks that Learn to Pronounce English Text

by Terrence J. Sejnowski, Charles R. Rosenberg - COMPLEX SYSTEMS , 1987
"... This paper describes NETtalk, a class of massively-parallel network systems that learn to convert English text to speech. The memory representations for pronunciations are learned by practice and are shared among many processing units. The performance of NETtalk has some similarities with observed h ..."
Abstract - Cited by 549 (5 self) - Add to MetaCart
task, but differ completely at the levels of synaptic strengths and single-unit responses. However, hierarchical clustering techniques applied to NETtalk reveal that these different networks have similar internal representations of letter-to-sound correspondences within groups of processing units

Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions

by Kim T. Simons, Charles Kooperberg, Enoch Huang, David Baker - J. MOL. BIOL , 1997
"... We explore the ability of a simple simulated annealing procedure to assemble native-like structures from fragments of unrelated protein structures with similar local sequences using Bayesian scoring functions. Environment and residue pair specific contributions to the scoring functions appear as the ..."
Abstract - Cited by 393 (70 self) - Add to MetaCart
We explore the ability of a simple simulated annealing procedure to assemble native-like structures from fragments of unrelated protein structures with similar local sequences using Bayesian scoring functions. Environment and residue pair specific contributions to the scoring functions appear

Architectural Mismatch or Why it's hard to build systems out of existing parts

by David Garlan , Robert Allen, John Ockerbloom , 1995
"... Many would argue that future breakthroughs in software productivity will depend on our ability to combine existing pieces of software to produce new applications. An important step towards this goal is the development of new techniques to detect and cope with mismatches in the assembled parts. Some ..."
Abstract - Cited by 380 (10 self) - Add to MetaCart
Many would argue that future breakthroughs in software productivity will depend on our ability to combine existing pieces of software to produce new applications. An important step towards this goal is the development of new techniques to detect and cope with mismatches in the assembled parts. Some

Learning to detect unseen object classes by betweenclass attribute transfer

by Christoph H. Lampert, Hannes Nickisch, Stefan Harmeling - In CVPR , 2009
"... We study the problem of object classification when training and test classes are disjoint, i.e. no training examples of the target classes are available. This setup has hardly been studied in computer vision research, but it is the rule rather than the exception, because the world contains tens of t ..."
Abstract - Cited by 363 (5 self) - Add to MetaCart
of thousands of different object classes and for only a very few of them image, collections have been formed and annotated with suitable class labels. In this paper, we tackle the problem by introducing attribute-based classification. It performs object detection based on a human-specified high

Assembly of cell regulatory systems through protein interaction domains

by Tony Pawson, Piers Nash - Science , 2003
"... The sequencing of complete genomes provides a list that includes the proteins responsible for cellular regulation. However, this does not immediately reveal what these proteins do, nor how they are assembled into the molecular machines and functional networks that control cellular behavior. The regu ..."
Abstract - Cited by 277 (8 self) - Add to MetaCart
The sequencing of complete genomes provides a list that includes the proteins responsible for cellular regulation. However, this does not immediately reveal what these proteins do, nor how they are assembled into the molecular machines and functional networks that control cellular behavior

GAM: Genomic Assemblies Merger A Graph Based Method to Integrate Different Assemblies

by Alberto Casagr, Cristian Del Fabbro, Simone Scalabrin, Alberto Policriti
"... Abstract—Many software tools are currently available to solve the hard goal of assembling millions of fragments pro-duced in sequencing projects. Such a variety includes packages for long and short reads, generated by classical and next-generation sequencing technologies. Often the result produced b ..."
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of different assembler’s output and improve the overall quality of the genome assembly sequences, by merging the sequences produced by different assembly programs. Keywords-DNA assemblers; Improving genomic assemblies; Data integration

Learning by Watching: Extracting Reusable Task Knowledge from Visual Observation of Human Performance

by Yasuo Kuniyoshi, Masayuki Inaba, Hirochika Inoue - IEEE Transactions on Robotics and Automation , 1994
"... A novel task instruction method for future intelligent robots is presented. In our method, a robot learns reusable task plans by watching a human perform assembly tasks. Functional units and working algorithms for visual recognition and analysis of human action sequences are presented. The overall s ..."
Abstract - Cited by 298 (6 self) - Add to MetaCart
A novel task instruction method for future intelligent robots is presented. In our method, a robot learns reusable task plans by watching a human perform assembly tasks. Functional units and working algorithms for visual recognition and analysis of human action sequences are presented. The overall

Algorithmic Self-Assembly of DNA

by Erik Winfree , 1998
"... How can molecules compute? In his early studies of reversible computation, Bennett imagined an enzymatic Turing Machine which modified a hetero-polymer (such as DNA) to perform computation with asymptotically low energy expenditures. Adleman's recent experimental demonstration of a DNA computat ..."
Abstract - Cited by 156 (6 self) - Add to MetaCart
computation, using an entirely different approach, has led to a wealth of ideas for how to build DNA-based computers in the laboratory, whose energy efficiency, information density, and parallelism may have potential to surpass conventional electronic computers for some purposes. In this thesis, I examine one

Path integration and cognitive mapping in a continuous attractor neural network model

by Alexei Samsonovich, Bruce L. Mcnaughton - Journal of Neuroscience , 1997
"... A minimal synaptic architecture is proposed for how the brain might perform path integration by computing the next internal representation of self-location from the current representation and from the perceived velocity of motion. In the model, a place-cell assembly called a “chart ” contains a twod ..."
Abstract - Cited by 240 (4 self) - Add to MetaCart
A minimal synaptic architecture is proposed for how the brain might perform path integration by computing the next internal representation of self-location from the current representation and from the perceived velocity of motion. In the model, a place-cell assembly called a “chart ” contains a
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