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What is a hidden Markov model?

by Sean R. Eddy , 2004
"... Often, problems in biological sequence analysis are just a matter of putting the right label on each residue. In gene identification, we want to label nucleotides as exons, introns, or intergenic sequence. In sequence alignment, we want to associate residues in a query sequence with ho-mologous resi ..."
Abstract - Cited by 1344 (8 self) - Add to MetaCart
scoring answer is one thing, but what does the score mean, and how confident are we that the best answer, or any given part of it, is correct? A third issue is extensibility. The moment we perfect our ad hoc genefinder, we wish we had also modeled translational initiation consensus, alternative splicing

Eliciting self-explanations improves understanding

by Michelene T. H. Chi, Nicholas De Leeuw, Mei-hung Chiu, Christian Lavancher - Cognitive Science , 1994
"... Learning involves the integration of new information into existing knowledge. Generoting explanations to oneself (self-explaining) facilitates that integration process. Previously, self-explanation has been shown to improve the acquisition of problem-solving skills when studying worked-out examples. ..."
Abstract - Cited by 577 (22 self) - Add to MetaCart
the pretest to the posttest. Moreover, prompted students who generated o large number of self-explanations (the high explainers) learned with greater understanding than low explainers. Understanding was assessed by answering very complex questions and inducing the function of a component when it was only

Loopy belief propagation for approximate inference: An empirical study. In:

by Kevin P Murphy , Yair Weiss , Michael I Jordan - Proceedings of Uncertainty in AI, , 1999
"... Abstract Recently, researchers have demonstrated that "loopy belief propagation" -the use of Pearl's polytree algorithm in a Bayesian network with loops -can perform well in the context of error-correcting codes. The most dramatic instance of this is the near Shannon-limit performanc ..."
Abstract - Cited by 676 (15 self) - Add to MetaCart
Abstract Recently, researchers have demonstrated that "loopy belief propagation" -the use of Pearl's polytree algorithm in a Bayesian network with loops -can perform well in the context of error-correcting codes. The most dramatic instance of this is the near Shannon

Hidden Markov models for detecting remote protein homologies

by Kevin Karplus, Christian Barrett, Richard Hughey - Bioinformatics , 1998
"... A new hidden Markov model method (SAM-T98) for nding remote homologs of protein sequences is described and evaluated. The method begins with a single target sequence and iteratively builds a hidden Markov model (hmm) from the sequence and homologs found using the hmm for database search. SAM-T98 is ..."
Abstract - Cited by 462 (15 self) - Add to MetaCart
is also used to construct model libraries automatically from sequences in structural databases. We evaluate the SAM-T98 method with four datasets. Three of the test sets are fold-recognition tests, where the correct answers are determined by structural similarity. The fourth uses a curated database

Characterizing and Computing Semantically Correct Answers from Databases with Annotated Logic and Answer Sets

by Pablo Barceló, Leopoldo Bertossi, Loreto Bravo
"... A relational database may not satisfy certain integrity constraints (ICs) for several reasons. However most likely most of the information in it is still consistent with the ICs. The answers to queries that are consistent with the ICs can be considered sematically correct answers, and are characteri ..."
Abstract - Cited by 35 (23 self) - Add to MetaCart
A relational database may not satisfy certain integrity constraints (ICs) for several reasons. However most likely most of the information in it is still consistent with the ICs. The answers to queries that are consistent with the ICs can be considered sematically correct answers

Are Shaping Techniques the Correct Answer for the Control of Visually Guided Autonomous Robots?

by P. Gaussier, C. Joulain, A. Revel, J-. P. Banquet - University of Exeter , 1996
"... Motor Category first learning phase corridor following reflex Figure 8: A two levels perception-action association architecture, RMO1 is used by RMO2 as if it is a sensory output. Each level corresponds to the basic perception-action association architecture. 4 Navigation in an open environment ..."
Abstract - Cited by 6 (5 self) - Add to MetaCart
Motor Category first learning phase corridor following reflex Figure 8: A two levels perception-action association architecture, RMO1 is used by RMO2 as if it is a sensory output. Each level corresponds to the basic perception-action association architecture. 4 Navigation in an open environment The navigation in an open environment may a priori seem also more complex. Indeed, if we keep the approach developed in section 2 and 3, the problem is not here to find a single object, but a set of local views relevant for place recognition. This entails that the robot should "understand" the objects in its environment (for instance it must know if objects can move). Yet, an animal introduced in a room can learn how to reach a goal easily even without a complete understanding of all the objects. The PerAc architecture can be used to learn the association between a perceived place (represented by a set of local views and their angles in an absolute or a relative referential) and the direct...

"... then click on the correct answer": which way ahead for the field of CALL?

by Cornelia Tschichold
"... Abstract Despite the promise it holds, tutorial CALL has been marginalized within the CALL community. Where the computer is used solely as a tool, the beneficial effects of feedback for language learning are absent. Vocabulary would be one of the areas where tutorial CALL can be of great use to the ..."
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Abstract Despite the promise it holds, tutorial CALL has been marginalized within the CALL community. Where the computer is used solely as a tool, the beneficial effects of feedback for language learning are absent. Vocabulary would be one of the areas where tutorial CALL can be of great use to the individual learner. A small study on learning Welsh vocabulary shows some of the areas where feedback in vocabulary CALL could be improved.

Odpowiedź na zagadkę ze str. 508 Answer to the question page 508 Prawidłowa odpowiedź: C. Correct answer: C.

by Odpowiedê Na Zagadk
"... Answer to the question W moich zbiorach to już 32. pacjent z potwier-dzoną serologicznie jersiniozą(1,2). Podobne zmiany może spowodować kompylobakterioza, a  także – rzadko – salmonelloza, shigelloza czy Clostridium difficile. W tych trzech ostatnich jednostkach cho-robowych zazwyczaj nie występuje ..."
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Answer to the question W moich zbiorach to już 32. pacjent z potwier-dzoną serologicznie jersiniozą(1,2). Podobne zmiany może spowodować kompylobakterioza, a  także – rzadko – salmonelloza, shigelloza czy Clostridium difficile. W tych trzech ostatnich jednostkach cho-robowych zazwyczaj nie

Prime diagnosticity in short-term repetition priming: Is primed evidence discounted, even when it reliably indicates the correct answer

by Christoph T. Weidemann, David E. Huber, Richard M. Shiffrin, Christoph T. Weidemann, Department Of Psychology, Richard M. Shiffrin, To Richard M. Shiffrin, David E - Journal of Experimental Psychology: Learning, Memory, & Cognition , 2008
"... The authors conducted 4 repetition priming experiments that manipulated prime duration and prime diagnosticity in a visual forced-choice perceptual identification task. The strength and direction of prime diagnosticity produced marked effects on identification accuracy, but those effects were resist ..."
Abstract - Cited by 9 (5 self) - Add to MetaCart
The authors conducted 4 repetition priming experiments that manipulated prime duration and prime diagnosticity in a visual forced-choice perceptual identification task. The strength and direction of prime diagnosticity produced marked effects on identification accuracy, but those effects were resistant to subsequent changes of diagnosticity. Participants learned to associate different diagnosticities with primes of different durations but not with primes presented in different colors. Regardless of prime diagnosticity, preference for a primed alternative covaried negatively with prime duration, suggesting that even for diagnostic primes, evidence discounting remains an important factor. A computational model, with the assumption that adaptation to the statistics of the experiment modulates the level of evidence discounting, accounted for these results.

of a type 1 error. I hope I have correctly answered Drs

by Tetsuro Oshika, Intravitreal Triamcinolone, Miyamoto N, Iossifov D, Metge F, Behar-cohen F. Early
"... Miyamoto et al1 show that intravitreal triamcinolone reduces macular edema as early as 1 hour after injection. They suggest that the time pattern demands that nongenomic mechanisms must be involved in the therapeutic effect of triamcinolone on retinal edema. Vasogenic edema in all tissues, including ..."
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Miyamoto et al1 show that intravitreal triamcinolone reduces macular edema as early as 1 hour after injection. They suggest that the time pattern demands that nongenomic mechanisms must be involved in the therapeutic effect of triamcinolone on retinal edema. Vasogenic edema in all tissues, including the retina, may be understood in terms of Starling’s law, 2,3 by which the balance of hydrostatic and oncotic pressure differences between vascular and tissue compartments determines the formation or disappearance of edema. Triamcinolone has generally been thought to influence capillary permeability and, thereby, the oncotic pressure gradient between vessel and tissue, and little attention has been paid to possible hemodynamic effects of the drug. However, Paques et al4 have recently reported that retinal vessel tortuosity decreases after intravitreal triamcinolone injection. Retinal vessel length, tortuosity, and diameter change together, and a decrease in tortuosity (length) is associated with a reduction in vessel diameter. 4–6 The early nongenomic effect that Miyamoto et al predict may well be the hemodynamic effect, by which triamcinolone induces retinal vasoconstriction and thereby reduces the hydrostatic pressure in the capillaries and reduces edema according to the hydrostatic pressure arm of Starling’s law. 2,3 The genomic effects of the corticosteroid, which decreases the permeability of retinal capillaries, will later affect the oncotic arm of Starling’s law and further reduce edema. 2 Both hydrostatic and oncotic pressure changes need to be considered to understand the mechanism of edema treatment fully.
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