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740
Weeder Web: discovery of transcription factor binding sites in a set of sequences from co-regulated genes
- Nucleic Acids Res
, 2004
"... One of the greatest challenges that modern molecular biology is facing is the understanding of the complex mechanisms regulating gene expression. A fundamental step in this process requires the characterization of regulatory motifs playing key roles in the regulation of gene expression at transcript ..."
Abstract
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Cited by 145 (2 self)
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One of the greatest challenges that modern molecular biology is facing is the understanding of the complex mechanisms regulating gene expression. A fundamental step in this process requires the characterization of regulatory motifs playing key roles in the regulation of gene expression
Detection of Co-regulated Genes by Comparative Analysis of Microbial Genomes
"... Introduction Rapid accumulation of genomic sequences is giving us a new opportunity to investigate and understand intricate biological systems, which may be represented as networks of genes and gene products. Several new experimental methods such as DNA microarray technology would be utilized to pr ..."
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to produce a huge amount of expression profiles and to determine correlated expression of genes in a wide variety of cells. The informatics based approaches should take large parts in this research area of functional genomics. Especially computational techniques to predict co-regulated genes must
Detection of Co-regulated Genes by Comparative Analysis of Microbial Genomes
"... Introduction Rapid accumulation of genomic sequences is giving us a new opportunitytoinvestigate and understand intricate biological systems, whichmay be represented as networks of genes and gene products. Several new experimental methods such as DNA microarray technology would be utilized to produ ..."
Abstract
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to produce a huge amount of expression profiles and to determine correlated expression of genes in a wide variety of cells. The informatics based approaches should take large parts in this research area of functional genomics. Especially computational techniques to predict co-regulated genes must
Cdx4 and Menin Co-Regulate Hoxa9 Expression in
"... Background. Transcription factor Cdx4 and transcriptional coregulator menin are essential for Hoxa9 expression and normal hematopoiesis. However, the precise mechanism underlying Hoxa9 regulation is not clear. Methods and Findings. Here, we show that the expression level of Hoxa9 is correlated with ..."
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Background. Transcription factor Cdx4 and transcriptional coregulator menin are essential for Hoxa9 expression and normal hematopoiesis. However, the precise mechanism underlying Hoxa9 regulation is not clear. Methods and Findings. Here, we show that the expression level of Hoxa9 is correlated
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
"... Abstract — Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper presents an innovative Collateral-Fuzzy Gene Regulatory Network Reconstruction (CF-GeNe) framework for Gene Regulato ..."
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Cited by 1 (0 self)
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-established fuzzy cmeans algorithm, with the model adapting to the data distribution by automatically determining key parameters, like the number of clusters. Empirical results confirm that the CMVE-based CF-GeNe paradigm infers the majority of co-regulated links even in the presence of large numbers of missing
Reverse engineering of regulatory networks in human B cells.
- Nat. Genet.
, 2005
"... Cellular phenotypes are determined by the differential activity of networks linking coregulated genes. Available methods for the reverse engineering of such networks from genome-wide expression profiles have been successful only in the analysis of lower eukaryotes with simple genomes. Using a new m ..."
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Cited by 178 (2 self)
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Cellular phenotypes are determined by the differential activity of networks linking coregulated genes. Available methods for the reverse engineering of such networks from genome-wide expression profiles have been successful only in the analysis of lower eukaryotes with simple genomes. Using a new
Synapse elimination and learning rules co-regulated by MHC class I H2-Db. Nature [Epub ahead of print
, 2014
"... The formation of precise connections between retina and LGN involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the MHC Class I (MHCI) molecule H2-Db is necessary and sufficient for synapse elimination in the retinogeniculate sy ..."
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Cited by 2 (0 self)
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system. In mice lacking both H2-Kb and H2-Db (KbDb−/−) despite intact retinal activity and basal synaptic transmission, the developmentally-regulated decrease in functional convergence of retinal ganglion cell synaptic inputs to LGN neurons fails and eye-specific layers do not form. Neuronal expression
The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity. PLoS One 2012
"... TNF-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) ligand family that exerts its apoptotic activity in human cells by binding to two transmembrane receptors, TRAILR1 and TRAILR2. In cells co-expressing both receptors the particular contribution of either pro ..."
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Cited by 1 (0 self)
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TNF-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) ligand family that exerts its apoptotic activity in human cells by binding to two transmembrane receptors, TRAILR1 and TRAILR2. In cells co-expressing both receptors the particular contribution of either
Materials for an exploratory theory of the network society.
- The British Journal of Sociology
, 2000
"... ABSTRACT This article aims at proposing some elements for a grounded theor y of the network society. The network society is the social structure characteristic of the Information Age, as tentatively identi ed by empirical, cross-cultural investigation. It permeates most societies in the world, in v ..."
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Cited by 122 (0 self)
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as the project is nished. Major corporations work in a strategy of changing alliances and partnerships, speci c to a given product, process, time, and space. Furthermore, these co-operations are based increasingly on sharing of information. These are information networks, which, in the limit, link up suppliers
Mother– and father–child mutuality in Anglo and Indian British families: A link with lower externalizing problems
- Journal of Abnormal Child Psychology
, 2004
"... The establishment and maintenance of a mutually responsive and emotionally warm parent-child relationship--what we refer to in this paper as mutuality--is one of the foundations of dyadic coregulation of behaviors, emotions, and cognitions. This, in turn, is critical to the development of children&a ..."
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Cited by 9 (0 self)
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's self-regulation (Kochanska, 1997; Maccoby, 1992). Difficulties in self-regulation of behavioral, emotional, and cognitive states that arise from problems in coregulation in dyadic interaction, are key components in the development of behavioral and emotional problems in childhood
Results 1 - 10
of
740
