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Apoptosis: a Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics

by J. F. R. Kerr, A. H. Wyllie, A. R. Curriet - Br. J. Cancer , 1972
"... Summary.-The term apoptosis is proposed for a hitherto little recognized mechanism of controlled cell deletion, which appears to play a complementary but opposite role to mitosis in the regulation of animal cell populations. Its morphological features suggest that it is an active, inherently program ..."
Abstract - Cited by 641 (6 self) - Add to MetaCart
Summary.-The term apoptosis is proposed for a hitherto little recognized mechanism of controlled cell deletion, which appears to play a complementary but opposite role to mitosis in the regulation of animal cell populations. Its morphological features suggest that it is an active, inherently

The Advantages of Evolutionary Computation

by David B. Fogel , 1997
"... Evolutionary computation is becoming common in the solution of difficult, realworld problems in industry, medicine, and defense. This paper reviews some of the practical advantages to using evolutionary algorithms as compared with classic methods of optimization or artificial intelligence. Specific ..."
Abstract - Cited by 541 (6 self) - Add to MetaCart
and optimization mechanism. Evolved biota demonstrate optimized complex behavior at every level: the cell, the organ, the individual, and the population. The problems that biological species have solved are typified by chaos, chance, temporality, and nonlinear interactivities. These are also characteristics

Competitive mechanisms subserve attention in macaque areas V2 and V4

by John H. Reynolds, Leonardo Chelazzi, Robert Desimone - Journal of Neuroscience , 1989
"... It is well established that attention modulates visual processing in extrastriate cortex. However, the underlying neural mechanisms are unknown. A consistent observation is that attention has its greatest impact on neuronal responses when multiple stimuli appear together within a cell’s receptive fi ..."
Abstract - Cited by 370 (14 self) - Add to MetaCart
It is well established that attention modulates visual processing in extrastriate cortex. However, the underlying neural mechanisms are unknown. A consistent observation is that attention has its greatest impact on neuronal responses when multiple stimuli appear together within a cell’s receptive

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

by Jennifer Nichols, Branko Zevnik, Daniela Klewe-nebenius, Ian Chambers - Cell , 1998
"... cell types, including germ cells. The ICM and its succes-sor the epiblast are highly regulative stem cell popula-tions that can adjust to various perturbations including major alterations in cell number and cell position (Hogan et al., 1994). The pool of stem cells remains pluripotent ..."
Abstract - Cited by 279 (14 self) - Add to MetaCart
cell types, including germ cells. The ICM and its succes-sor the epiblast are highly regulative stem cell popula-tions that can adjust to various perturbations including major alterations in cell number and cell position (Hogan et al., 1994). The pool of stem cells remains pluripotent

situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

by Joshy Jacob, Garnett Kelsoe , 1991
"... In the genetically restricted response that follows immunization with (4-hydroxy-3-nitrophenyl)acetyl coupled to protein carriers, two distinct populations of B cells are observed in the spleens of C57BL/6 mice. By 48 h postimmunization, loci of antigen-binding B cells appear along the periphery of ..."
Abstract - Cited by 171 (6 self) - Add to MetaCart
In the genetically restricted response that follows immunization with (4-hydroxy-3-nitrophenyl)acetyl coupled to protein carriers, two distinct populations of B cells are observed in the spleens of C57BL/6 mice. By 48 h postimmunization, loci of antigen-binding B cells appear along the periphery

Cell Population Tracking and Lineage Construction with Spatiotemporal Context

by Kang Li , Eric D. Miller , Mei Chen , Takeo Kanade , Lee E. Weiss , Phil G. Campbell , 2009
"... Automated visual-tracking of cell populations in vitro using time-lapse phase contrast microscopy enables quantitative, systematic and high-throughput measurements of cell behaviors. These measurements include the spatiotemporal quantification of cell migration, mitosis, apoptosis, and the reconstru ..."
Abstract - Cited by 80 (10 self) - Add to MetaCart
Automated visual-tracking of cell populations in vitro using time-lapse phase contrast microscopy enables quantitative, systematic and high-throughput measurements of cell behaviors. These measurements include the spatiotemporal quantification of cell migration, mitosis, apoptosis

Blood monocytes consist of two principal subsets with distinct migratory properties

by Frederic Geissmann, Steffen Jung, Dan R. Littman - Immunity , 2003
"... Peripheral blood monocytes are a heterogeneous population of circulating leukocytes. Using a murine adop-tive transfer system to probe monocyte homing and differentiation in vivo, we identified two functional subsets among murine blood monocytes: a short-lived CX3CR1loCCR2�Gr1 � subset that is activ ..."
Abstract - Cited by 342 (5 self) - Add to MetaCart
Peripheral blood monocytes are a heterogeneous population of circulating leukocytes. Using a murine adop-tive transfer system to probe monocyte homing and differentiation in vivo, we identified two functional subsets among murine blood monocytes: a short-lived CX3CR1loCCR2�Gr1 � subset

Modelling the movement of interacting cell populations

by Kevin J. Painter, Jonathan A. Sherratt , 2003
"... Mathematical modelling of cell movement has traditionally focussed on a single population of cells, often moving in response to various chiouss and environmental cues. Inthfi paper, we consider models for movement in two or more interacting cell populations. We begin by discussing intuitive ideas un ..."
Abstract - Cited by 11 (2 self) - Add to MetaCart
Mathematical modelling of cell movement has traditionally focussed on a single population of cells, often moving in response to various chiouss and environmental cues. Inthfi paper, we consider models for movement in two or more interacting cell populations. We begin by discussing intuitive ideas

Proliferation of mutators in a cell population

by E F Mao, L Lane, J Lee, J H Miller, Emily F. Mao, Laura Lane, Jean Lee, Jeffrey, H. Miller - J , 1997
"... Updated information and services can be found at: ..."
Abstract - Cited by 60 (4 self) - Add to MetaCart
Updated information and services can be found at:

DRUG TARGETS IN PROLIFERATING CELL POPULATION DYNAMIC MODELS

by Er Lorz, Benoît Perthame
"... Modelling targets for anticancer drug control optimisation in physiologically structured cell population models ..."
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Modelling targets for anticancer drug control optimisation in physiologically structured cell population models
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