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Distribution of multiple sclerosis

by Alastair Compston, Alasdair Coles , 1998
"... Multiple sclerosis is primarily an infl ammatory disorder of the brain and spinal cord in which focal lymphocytic infi ltration leads to damage of myelin and axons. Initially, infl ammation is transient and remyelination occurs but is not durable. Hence, the early course of disease is characterised ..."
Abstract - Cited by 180 (3 self) - Add to MetaCart
of the cerebrospinal fl uid). Multiple sclerosis is triggered by environmental factors in individuals with complex genetic-risk profi les. Licensed disease modifying agents reduce the frequency of new episodes but do not reverse fi xed defi cits and have questionable eff ects on the long-term accumulation

The e¤ect of the Chilean Pension Reform on Wealth Accumulation

by Ximena Quintanilla, Jel E , 2007
"... Chile went through a major pension system reform in 1981, replac-ing the state managed pay-as-you-go system by a privately-managed fully funded scheme. The reform implied a rather important increase in ex-pected pension wealth for those who opted-out to the new arrangement. We investigate the extent ..."
Abstract - Cited by 1 (1 self) - Add to MetaCart
the extent to which households substitute this increase by decreasing accumulation of other wealth. As the decision to either stay in the old system or opt-out to the new one was not random, we follow an instrumental variable approach that allow us to overcome the unobserved heterogeneity problem. Using data

Correlated mutations contain information about protein-protein interaction

by Florencio Pazos, Manuela Helmer-citterich, Gabriele Ausiello, Alfonso Valencia, Autoânoma Cantoblanco - J. Mol. Biol , 1997
"... Many proteins have evolved to form speci®c molecular complexes and the speci®city of this interaction is essential for their function. The network of the necessary inter-residue contacts must consequently constrain the protein sequences to some extent. In other words, the sequence of an interacting ..."
Abstract - Cited by 141 (12 self) - Add to MetaCart
protein must re¯ect the consequence of this process of adaptation. It is reasonable to assume that the sequence changes accumulated during the evolution of one of the interacting proteins must be compensated by changes in the other. Here we apply a method for detecting correlated changes in multiple

Population Changes and Capital Accumulation: The Aging of the Baby Boom

by José-Víctor Rios-Rull , 2000
"... In most western countries the population is aging. The baby boom is approaching middle age and drastic changes in the aggregate behavior of consumption and savings might be foreseen due to the nature of this demographic change. This paper assesses the quantitative implications of the aging proces ..."
Abstract - Cited by 44 (1 self) - Add to MetaCart
of the population is small. If, however, the demographic process is such that fertility patterns remain at their current low levels, then the e#ects of the aging of the baby boom are very large. The contribution of general equilibrium e#ects is to exacerbate the reduction of savings since popualtion aging tends

Specialization, Factor Accumulation and Development

by Doireann Fitzgerald, Juan Carlos Hallaky - Journal of International Economics, December 2004
"... We estimate the e¤ect of factor proportions on the pattern of manufacturing spe-cialization in a cross-section of OECD countries, taking into account that factor accu-mulation responds to productivity. We show that the failure to control for productivity di¤erences produces biased estimates. Our mod ..."
Abstract - Cited by 7 (1 self) - Add to MetaCart
We estimate the e¤ect of factor proportions on the pattern of manufacturing spe-cialization in a cross-section of OECD countries, taking into account that factor accu-mulation responds to productivity. We show that the failure to control for productivity di¤erences produces biased estimates. Our

Foreign Asset Accumulation, Macroeconomic Policies and

by Gaowang Wang, Heng-fu Zou , 2012
"... The paper studies …scal policy, monetary policy and the exchange-rate the-ory in a Viner-Zou monetary model of mercantilism. It is shown that, except for government consumption, permanent increases in the mercantilist sentiments, monetary growth rate, consumption tax, and foreign exchange interventi ..."
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intervention have positive e¤ects on consumption and foreign asset accumulation in the long run; and, in the short run, except for negative e¤ects on both consumption and foreign asset accumulation of government consumption and positive e¤ects on both consumption and foreign asset accumulation of foreign

The e¤ect of environmental policy on collusion

by Hassan Benchekrouna, Amrita Ray Chaudhurib , 2008
"... This paper examines how the implementation of a carbon tax a¤ects collusive behaviour amongst polluting …rms. We use a dynamic scenario where pollution is allowed to accumulate into a stock over time. We examine the following two scenarios: (i) the carbon tax rate is an exogenously given constant, t ..."
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This paper examines how the implementation of a carbon tax a¤ects collusive behaviour amongst polluting …rms. We use a dynamic scenario where pollution is allowed to accumulate into a stock over time. We examine the following two scenarios: (i) the carbon tax rate is an exogenously given constant

Civil Con ict and Human Capital Accumulation: The Long Term E ects of Political Violence in Perú

by Gianmarco León
"... This paper provides empirical evidence of the long- and short-term e ects of exposure to political violence on human capital accumulation. Using a novel data set that registers all the violent acts and fatalities during the Peruvian civil con ict, I exploit the variation in con ict location and birt ..."
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This paper provides empirical evidence of the long- and short-term e ects of exposure to political violence on human capital accumulation. Using a novel data set that registers all the violent acts and fatalities during the Peruvian civil con ict, I exploit the variation in con ict location

Financial Integration, Productivity and Capital Accumulation

by Alessandra Bon…glioli Y , 2007
"... Understanding the mechanism through which …nancial globalization a¤ects economic performance is crucial for evaluating the costs and bene…ts of opening …nancial markets. This paper is a …rst attempt at disentangling the e¤ects of …nancial integration on the two main determinants of economic performa ..."
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capital accumulation. I control for indirect e¤ects of …nancial globalization through …nancial development and banking and currency crises. While the evidence on …nancial depth as an indirect channel is weak, the results are more robust for …nancial crises: they depress both investments and TFP

Financial Integration, Productivity and Capital Accumulation

by Alessandra Bon Glioliy , 2008
"... Understanding the mechanism through which …nancial globalization a¤ects eco-nomic performance is crucial for evaluating the costs and bene…ts of opening …nancial markets. This paper is a …rst attempt at disentangling the e¤ects of …nancial inte-gration on the two main determinants of economic perfor ..."
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accumulation. I also control for indirect e¤ects of …nancial globalization through …nancial development and banking and currency crises. While nancial integration does not systematically increase domestic …nancial depth, it may raise the likelyhood of banking crises, though only to a minor extent. Yet
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