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Targeted disruption of Hoxd-10 affects mouse hindlimb development. Development 124
, 1997
"... Targeted disruption of the Hoxd-10 gene, a 5 ′ member of the mouse HoxD linkage group, produces mice with hindlimb-specific defects in gait and adduction. To determine the underlying causes of this locomotor defect, mutant mice were examined for skeletal, muscular and neural abnormalities. Mutant mi ..."
Abstract
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Cited by 8 (3 self)
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of spinal segments projecting nerve fibers through the sacral plexus to innervate the musculature of the hindlimb. Deletion of a hindlimb nerve was seen in some animals, and a shift was evident in the position of the lumbar lateral motor column. These observations suggest a role for the Hoxd-10 gene
Identification of a new vertebrate nucleoporin, Nup188, with the use of a novel organelle trap assay
- Mol. Biol. Cell
, 2000
"... The study of the nuclear pore in vertebrates would benefit from a strategy to directly identify new nucleoporins and interactions between those nucleoporins. We have developed a novel two-step "organelle trap" assay involving affinity selection and in vitro pore assembly. In the first ste ..."
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Cited by 7 (2 self)
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Nucleoporins Vol. 11, October 2000 3389 noprecipitated only trace amounts of p190 ( Identification of the Vertebrate Nucleoporin, Nup188 To identify p170, we purified p170 protein from large-scale preparations of low-salt XE. We found that Nup93 and its associated proteins, Nup205 and p170, once bound to a B
Identification of Two Evolutionarily Conserved 5 ’ cis- Elements Involved in Regulating Spatiotemporal
"... Proper development of vertebrate embryos depends not only on the crucial funtions of key evolutionarily conserved transcriptional regulators, but also on the precisely spatiotemporal expression of these transcriptional regulators. The mouse Nolz-1/Znf503/Zfp503 gene is a mammalian member of the cons ..."
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organs during mouse embryogensis. UREA directed LacZ expression preferentially in selective regions of developing central nervous system, including the forebrain, hindbrain and spinal cord, whereas UREB directed LacZ expression mainly in other developing tissue organs such as the Nolz-1 expressing
Review
"... The differential diagnosis of longitudinally extensive transverse myelitis JL Kitley, MI Leite, JS George and JA Palace Longitudinally extensive transverse myelitis refers to florid and widespread inflammation of the spinal cord causing T2 hyperintensity on spinal magnetic resonance imaging that is ..."
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that is seen to extend over three or more vertebral segments. Whilst rare, longitudinally extensive transverse myelitis is clinically important as it can lead to catastrophic morbidity, and a group of these patients are at risk of further attacks. Early identification and establishment of the underlying
Review
"... The differential diagnosis of longitudinally extensive transverse myelitis JL Kitley, MI Leite, JS George and JA Palace Longitudinally extensive transverse myelitis refers to florid and widespread inflammation of the spinal cord causing T2 hyperintensity on spinal magnetic resonance imaging that is ..."
Abstract
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that is seen to extend over three or more vertebral segments. Whilst rare, longitudinally extensive transverse myelitis is clinically important as it can lead to catastrophic morbidity, and a group of these patients are at risk of further attacks. Early identification and establishment of the underlying
04_may
"... Materials and Methods Animal Model The surgically induced medial meniscal tear procedure is performed on 300-400 gram rats. The medial collateral ligament is transected and the medial meniscus is reflected medially toward the femur and then cut. The cut is made through the full thickness to simulat ..."
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of the brain. Spinal cord is removed by severing the vertebral column at the base of the skull near the last lumbar vertebra. The cord is forced out of the vertebral column by injecting phosphate buffered saline (PBS) into the lumbar vertebral opening so the cord ejects out of the wider cervical vertebral
Introduction Architecture of enteric neural circuits involved in intestinal motility
, 2008
"... Intestinal motility is a field that has a high relevance for interpreting health of individuals and is the subject of a large number of publications over more than 100 years. Yet it remains an ill defined collection of descriptions barely relevant to what actually happens in a living higher organis ..."
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activity persisted in isolated segments of intestine. Architecture of enteric neural circuits involved in intestinal motility 6 Propulsion, described as peristalsis, could then be attributed to enteric reflexes (myenteric reflex or peristaltic reflex). The history of the identification of motor
Newt Opportunities for Understanding the Dedifferentiation Process
"... Urodele amphibians, such as the newt Notophthalmus viridescens, have the unique ability to regenerate limbs, spinal cord, eye structures, and many vital organs through a process called epimorphic regeneration. Although the cellular basis of regeneration has been studied in detail, we know relativel ..."
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Urodele amphibians, such as the newt Notophthalmus viridescens, have the unique ability to regenerate limbs, spinal cord, eye structures, and many vital organs through a process called epimorphic regeneration. Although the cellular basis of regeneration has been studied in detail, we know
