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The Rat Genome Database 2009: variation, ontologies and pathways
- Nucleic Acids Res
, 2009
"... gies and pathways ..."
doi:10.1093/nar/gkn842 The Rat Genome Database 2009: variation, ontologies and pathways
, 2008
"... The Rat Genome Database (RGD, ..."
Original Article Ontology searching and browsing at the Rat Genome Database
"... The Rat Genome Database (RGD) is the premier repository of rat genomic and genetic data and currently houses over 40 000 rat gene records, as well as human and mouse orthologs, 1857 rat and 1912 human quantitative trait loci (QTLs) and 2347 rat strains. Biological information curated for these data ..."
Abstract
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The Rat Genome Database (RGD) is the premier repository of rat genomic and genetic data and currently houses over 40 000 rat gene records, as well as human and mouse orthologs, 1857 rat and 1912 human quantitative trait loci (QTLs) and 2347 rat strains. Biological information curated for these data
Original article PhenoMiner: quantitative phenotype curation at the rat genome database
"... The Rat Genome Database (RGD) is the premier repository of rat genomic and genetic data and currently houses>40 000 rat gene records as well as human and mouse orthologs,>2000 rat and 1900 human quantitative trait loci (QTLs) records and>2900 rat strain records. Biological information curat ..."
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The Rat Genome Database (RGD) is the premier repository of rat genomic and genetic data and currently houses>40 000 rat gene records as well as human and mouse orthologs,>2000 rat and 1900 human quantitative trait loci (QTLs) records and>2900 rat strain records. Biological information
Enchytraeus albidus Microarray: Enrichment, Design, Annotation and Database (EnchyBASE)
"... Enchytraeus albidus (Oligochaeta) is an ecologically relevant species used as standard test organisms for risk assessment. Effects of stressors in this species are commonly determined at the population level using reproduction and survival as endpoints. The assessment of transcriptomic responses can ..."
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and pesticide exposures; 2) sequencing and characterization of all generated cDNA inserts; 3) development of a publicly available genomic database on E. albidus. A total of 2100 Expressed Sequence Tags (ESTs) were isolated, sequenced and assembled into 1124 clusters (947 singletons and 177 contigs). From
RESEARCH ARTICLE Endoplasmic Reticulum Stress in Heat- and Shake-Induced Injury in the Rat Small Intestine
"... We investigated the mechanisms underlying damage to rat small intestine in heat- and shake-induced stress. Eighteen Sprague-Dawley rats were randomly divided into a control group and a 3-day stressed group treated 2 h daily for 3 days on a rotary platform at 35°C and 60 r/min. Hematoxylin and eosin- ..."
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We investigated the mechanisms underlying damage to rat small intestine in heat- and shake-induced stress. Eighteen Sprague-Dawley rats were randomly divided into a control group and a 3-day stressed group treated 2 h daily for 3 days on a rotary platform at 35°C and 60 r/min. Hematoxylin and eosin
EMBnet.journal 18.B PostErs 151 A first RDF implementation of the COSMIC database on mutations in cancer
"... Within a living organism, genome and proteome variations may influence many molecular inter-actions and biochemical pathways, leading to deleterious effects in the proper activity of cells, tissues, and organs; ultimately, this may be the cause of many syndromes and diseases. It is now well known th ..."
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Within a living organism, genome and proteome variations may influence many molecular inter-actions and biochemical pathways, leading to deleterious effects in the proper activity of cells, tissues, and organs; ultimately, this may be the cause of many syndromes and diseases. It is now well known
BIOMEDICAL SEMANTICS
"... Background: The Pathway Ontology (PW) developed at the Rat Genome Database (RGD), covers all types of biological pathways, including altered and disease pathways and captures the relationships between them within the hierarchical structure of a directed acyclic graph. The ontology allows for the sta ..."
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Background: The Pathway Ontology (PW) developed at the Rat Genome Database (RGD), covers all types of biological pathways, including altered and disease pathways and captures the relationships between them within the hierarchical structure of a directed acyclic graph. The ontology allows
Transcriptome Analysis of the Hippocampus in Novel Rat Model of Febrile Seizures
"... Febrile seizures (FS) are the most common type of convulsive events in infants and young children, but the precise underlying genetic mechanism remains to be explored. To investigate the underlying pathogenic factors in FS and subsequent epilepsy, alterations in gene expression between the two new s ..."
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strains of rats (hyperthermia-prone [HP] vs hyperthermia-resistant [HR]), were investigated by using the Whole Rat Genome Oligo Microarray. This process identified 1,140 differentially expressed genes (DEGs; 602 upregulated and 538 downregulated), which were analyzed to determine significant Gene Ontology
doi:10.1155/2012/695898 Research Article Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of
"... Copyright © 2012 Daisuke Yoshihara et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Kidneys are enlarged by aberrant proliferat ..."
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pathways identified to be downregulated by PIOtreatment were related to cell cycle and proliferation, including EGF, PDGF and JNK pathways. Their relevant pathways were identified using the Kyoto Encyclopedia of Gene and Genomes database. Stearoyl-
Results 1 - 10
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27