Abstract. This paper introduces a system that processes clinical trials using a combination of natural language processing and database techniques. We pro-cess web-based clinical trial recruitment pages to extract semantic information reflecting eligibility criteria for potential participants. From

eligibility

To comprehend the results of a randomized, controlled trial (RCT), readers must understand its design, conduct, analysis, and inter-pretation. That goal can be achieved only through complete trans-parency from authors. Despite several decades of educational ef-forts, the reporting of RCTs needs

boosting algorithm for combining preferences called RankBoost. We also describe an efficient implementation of the algorithm for certain natural cases. We discuss two experiments we carried out to assess the performance of RankBoost. In the first experiment, we used the algorithm to combine different WWW

by querying the sample image and finding all similar neighborhoods. The degree of randomness is controlled by a single perceptually intuitive parameter. The method aims at preserving as much local structure as possible and produces good results for a wide variety of synthetic and real-world textures. 1

clinical phenomena, suggest that affective judgments may be fairly inde-pendent of, and precede in time, the sorts of percep-tual and cognitive operations commonly assumed to be the basis of these affective judgments. Affective re-actions to stimuli are often the very first reactions of the organism

Existing models for describing a process (such as a business process or a software development process) tend to focus on the \what " or the \how " of the process. For example, a health insurance claim process would typically be described in terms of a number of steps for assessing

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The term Linked Data refers to a set of best practices for publishing and connecting structured data on the Web. These best practices have been adopted by an increasing number of data providers over the last three years, leading to the creation of a global data space containing billions of assertions- the Web of Data. In this article we present the concept and technical principles of Linked Data, and situate these within the broader context of related technological developments. We describe progress to date in publishing Linked Data on the Web, review applications that have been developed to exploit the Web of Data, and map out a research agenda for the Linked Data community as it moves forward.

The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits the execution time of the BLAST programs to be decreased substantially while enhancing their sensitivity to weak similarities. A new criterion for triggering the extension of word hits, combined with a new heuristic for generating gapped alignments, yields a gapped BLAST program that runs at approximately three times the speed of the original. In addition, a method is introduced for automatically combining statistically significant alignments produced by BLAST into a position-specific score matrix, and searching the database using this matrix. The resulting Position-Specific Iterated BLAST (PSIBLAST) program runs at approximately the same speed per iteration as gapped BLAST, but in many cases is much more sensitive to weak but biologically relevant sequence similarities. PSI-BLAST is used to uncover several new and interesting members of the BRCT superfamily.