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Estimating recombination rate distribution by optimal quantization
 Proceesings of IEEE Computational Systems Bioinformatics Conference, 2003
, 2003
"... Evolution biologists are interested in a high resolution recombination map that depicts accurately how often a recombination event occurs at a specific location in the genome. With the availability of human genome physical map and fast sequencing technology, people start to estimate recombination ra ..."
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Cited by 1 (0 self)
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rate distributions. We obtain recombination rate distribution functions for all the chromosomes in the human genome using an optimal quantization method. In this method, we are able to control explicitly 1 overfitting/underfitting. The obtained piecewise constant recombination rate distribution
Estimating the Support of a HighDimensional Distribution
, 1999
"... Suppose you are given some dataset drawn from an underlying probability distribution P and you want to estimate a "simple" subset S of input space such that the probability that a test point drawn from P lies outside of S is bounded by some a priori specified between 0 and 1. We propo ..."
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Cited by 766 (29 self)
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Suppose you are given some dataset drawn from an underlying probability distribution P and you want to estimate a "simple" subset S of input space such that the probability that a test point drawn from P lies outside of S is bounded by some a priori specified between 0 and 1. We
Quantization Index Modulation: A Class of Provably Good Methods for Digital Watermarking and Information Embedding
 IEEE TRANS. ON INFORMATION THEORY
, 1999
"... We consider the problem of embedding one signal (e.g., a digital watermark), within another "host" signal to form a third, "composite" signal. The embedding is designed to achieve efficient tradeoffs among the three conflicting goals of maximizing informationembedding rate, mini ..."
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Cited by 495 (15 self)
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We consider the problem of embedding one signal (e.g., a digital watermark), within another "host" signal to form a third, "composite" signal. The embedding is designed to achieve efficient tradeoffs among the three conflicting goals of maximizing informationembedding rate
Estimating Continuous Distributions in Bayesian Classifiers
 In Proceedings of the Eleventh Conference on Uncertainty in Artificial Intelligence
, 1995
"... When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated by a single Gaussian. In this paper we abandon the normality ..."
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Cited by 489 (2 self)
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distribution with a single Gaussian; and using nonparametric kernel density estimation. We observe large reductions in error on several natural and artificial data sets, which suggests that kernel estimation is a useful tool for learning Bayesian models. In Proceedings of the Eleventh Conference on Uncertainty
DISTRIBUTED SYSTEMS
, 1985
"... Growth of distributed systems has attained unstoppable momentum. If we better understood how to think about, analyze, and design distributed systems, we could direct their implementation with more confidence. ..."
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Cited by 755 (1 self)
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Growth of distributed systems has attained unstoppable momentum. If we better understood how to think about, analyze, and design distributed systems, we could direct their implementation with more confidence.
Optimization Flow Control, I: Basic Algorithm and Convergence
 IEEE/ACM TRANSACTIONS ON NETWORKING
, 1999
"... We propose an optimization approach to flow control where the objective is to maximize the aggregate source utility over their transmission rates. We view network links and sources as processors of a distributed computation system to solve the dual problem using gradient projection algorithm. In thi ..."
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Cited by 690 (64 self)
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We propose an optimization approach to flow control where the objective is to maximize the aggregate source utility over their transmission rates. We view network links and sources as processors of a distributed computation system to solve the dual problem using gradient projection algorithm
Genetic Algorithms for Multiobjective Optimization: Formulation, Discussion and Generalization
, 1993
"... The paper describes a rankbased fitness assignment method for Multiple Objective Genetic Algorithms (MOGAs). Conventional niche formation methods are extended to this class of multimodal problems and theory for setting the niche size is presented. The fitness assignment method is then modified to a ..."
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Cited by 610 (15 self)
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to allow direct intervention of an external decision maker (DM). Finally, the MOGA is generalised further: the genetic algorithm is seen as the optimizing element of a multiobjective optimization loop, which also comprises the DM. It is the interaction between the two that leads to the determination of a
ModelBased Clustering, Discriminant Analysis, and Density Estimation
 JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
, 2000
"... Cluster analysis is the automated search for groups of related observations in a data set. Most clustering done in practice is based largely on heuristic but intuitively reasonable procedures and most clustering methods available in commercial software are also of this type. However, there is little ..."
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Cited by 557 (28 self)
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for modelbased clustering that provides a principled statistical approach to these issues. We also show that this can be useful for other problems in multivariate analysis, such as discriminant analysis and multivariate density estimation. We give examples from medical diagnosis, mineeld detection, cluster
Minimum Error Rate Training in Statistical Machine Translation
, 2003
"... Often, the training procedure for statistical machine translation models is based on maximum likelihood or related criteria. A general problem of this approach is that there is only a loose relation to the final translation quality on unseen text. In this paper, we analyze various training cri ..."
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Cited by 663 (7 self)
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criteria which directly optimize translation quality.
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