Treatment plan optimization for rotating-shield brachytherapy

The compressive sensing (CS) framework aims to ease the burden on analog-to-digital converters (ADCs) by exploiting inherent structure in natural and man-made signals. It has been demon-strated that structured signals can be acquired with just a small number of linear measurements, on the order of the signal complexity. In practice, this enables lower sampling rates that can be more easily achieved by current hardware designs. The primary bottleneck that limits ADC sam-pling rates is quantization, i.e., higher bit-depths impose lower sampling rates. Thus, the decreased sampling rates of CS ADCs accommodate the otherwise limiting quantizer of conventional ADCs. In this thesis, we consider a different approach to CS ADC by shifting towards lower quantizer bit-depths rather than lower sampling rates. We explore the extreme case where each measurement is quantized to just one bit, representing its sign. We develop a new theoretical framework to analyze this extreme case and develop new algorithms for signal reconstruction from such coarsely quantized measurements. The 1-bit CS framework leads us to scenarios where it may be more appropriate to reduce bit-depth instead of sampling rate. We find that there exist two distinct regimes of operation that correspond to high/low signal-to-noise ratio (SNR). In the measurement

Sujet de la thèse: Dynamique quantique hors-équilibre et systèmes désordonnés pour des atomes ultrafroids bosoniques présentée par Bruno Sciolla pour obtenir le grade de Docteur de l’Université Paris-sud 11 Directeur de thèse: Henri Orland Thèse préparée sous la direction de Giulio Biroli