Babelomics has been running for more than one decade offering a user-friendly interface for the func-tional analysis of gene expression and genomic data. Here we present its fifth release, which includes sup-port for Next Generation Sequencing data including gene expression (RNA-seq), exome

. Throughout most of the 1990s, New Enterprise Associates had the highest betweenness centrality scores (standing "between" approximately 6% of all possible VC pairs), only to be overtaken by Intel Capital, the venture capital arm of Intel Corp, in 1999. 17 Since Venture Economics' data

interpretable simplivariate components. We present a new implementation of the recently introduced simplivariate models. In this implementation, the informative variation is described by multiplicative models that can adequately represent the relations between functional genomics data. Both a simulated and two

for at least 32% of the variance in liability. Common genetic variation has an important role in the etiology of schizophrenia, and larger studies will allow more detailed understanding of this disorder. significance RESULTS Results for Swedish samples We analyzed genome-wide SNP data in 5,001 schizophrenia

: The integrated access to primary genomics data, functional knowledge and analytical tools makes Genomics Portals platform a unique tool for interpreting results of new genomics experiments and for mining the vast amount of data stored in the Genomics Portals backend databases. Genomics Portals can be accessed

of new types of genome data, e.g., gene order and short interspersed nuclear elements (SINEs), for which MP may be more appropriate. Concern about the computational complexity of ML. Even on a given tree, optimizing the likelihood can be problematic (unlike with MP, for which Fitch's [1971b

Background: Detailed and comprehensive genome annotation can be considered a prerequisite for effective analysis and interpretation of omics data. As such, Gene Ontology (GO) annotation has become a well accepted framework for functional annotation. The genus Aspergillus comprises fungal species

A major challenge in interpreting the large volume of mutation data identified by next-generation sequencing (NGS) is to distinguish driver mutations from neutral passenger mutations to facilitate the identification of targetable genes and new drugs. Current approaches are primarily based

conformational changes, and assisting in the interpretation of structural experimental data, paying close attention to hybrid Trends in ENM development The agreement between the observed functional motions and the lowest frequency modes extracted with NMA is relatively well preserved independently of model

of newly generated data. The variety of biological sequence and functional information are stored in different online database, so getting annotation information of genome from different database is challenging task for reconstruction of pathways. Here we apply data integration approach to provide rich